Vincristine-induced acute neurotoxicity versus Guillain–Barré syndrome: a diagnostic dilemma |
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| Authors: | P. Gonzá lez Pé rez,A. Serrano-Pozo,E. Franco-Mací as,E. Montes-Latorre,F. Gó mez-Aranda, T. Campos |
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| Affiliation: | Department of Neurology and Clinical Neurophysiology;;and Department of Haematology, University Hospital Virgen del Rocío, Seville, Spain |
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| Abstract: | We report the case of a patient with acute lymphoblastic leukaemia who, after the initiation of treatment with vincristine (VCR), developed a fulminant motor polyradiculoneuropathy resembling an axonal variant of Guillain-Barré syndrome (GBS). This report shows that differentiating between axonal GBS and VCR-induced acute neurotoxicity may be a challenge for clinicians. |
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| Keywords: | chemotherapy Guillain-Barré syndrome leukaemia neurotoxicity vincristine |
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