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银黄含化片对咽炎模型兔C-反应蛋白及白细胞介素-6表达的影响
引用本文:张莉,王宝忠,白音夫. 银黄含化片对咽炎模型兔C-反应蛋白及白细胞介素-6表达的影响[J]. 中国医药, 2008, 3(12): 742-744
作者姓名:张莉  王宝忠  白音夫
作者单位:内蒙古医学院附属医院耳鼻喉科,呼和浩特,010050
基金项目:内蒙古自治区方然科学基金 
摘    要:目的探讨银黄含化片对咽炎模型兔C-反应蛋白(CRP)及白细胞介素-6(IL-6)表达的影响。方法选择20只日本大耳白兔,用彭氏造模法制造咽炎模型,免疫组织化学检测法分别检测造模前后及咽炎痊愈后的CRP及IL-6表达。结果造模前CRP检测血中含量低,IL-6为弱表达;造模成功后咽炎形成,CRP含量增高,IL-6表达增强;动物模型康复过程中,随着咽炎的好转,CRP检测血中含量逐渐降低,此时IL-6表现为强表达。结论CRP和IL-6是炎症反应的标记物,在咽炎发病中起重要作用,银黄含化片有一定的治疗作用。

关 键 词:咽炎  银黄含化片  C-反应蛋白  白细胞介素-6

Relationship between the tablet of Yinhuang and C-reactive protein.intedeukin-6 in pharyngitis rabbit model
ZHANG Li,WANG Bao-zhong,BAI Yin-fu. Relationship between the tablet of Yinhuang and C-reactive protein.intedeukin-6 in pharyngitis rabbit model[J]. China Medicine, 2008, 3(12): 742-744
Authors:ZHANG Li  WANG Bao-zhong  BAI Yin-fu
Affiliation:. Departement of Ear-Nose-Throat, First Affiliated Hospital of Inner Mongolia Medical College ( Huhhot 010050, China)
Abstract:Objective To study the expression of C-reactive protein,interleukin-6 in the pharyngitis rabbit model with the tablet of Yinhuang.Methotis Choose 20 rabbits,use the method of Pengg to make the pharyngitis rabbit model.with Immunohistochemical detection to determine CRP and IL-6 before and after the recovery pharyngitis.Results CRP testing before making model content in the blood low,IL-6 is a weak expression,after modcling success,CRP levels increased,IL-6 expression.with the improvement of pharyngitis,blood levels of CRP gradually reduced and IL-6 showed strong expression.Conclusion CRP and IL-6 ale markers of inflammatory response,which play important role in the process of the pharyngitis rabbit model,the tablet of Yinhuang has a certain therapeutic effect.
Keywords:Pharyngitis  Yinhuang of tablets  C-reactive protein  Interleukin-6
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