| 抗生素联合抗菌作用试验观察 |
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| 引用本文： | 国建秋,徐卫宾. 抗生素联合抗菌作用试验观察[J]. 药学实践杂志, 2004, 22(2): 81-82 |
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| 作者姓名： | 国建秋 徐卫宾 |
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| 作者单位： | 山东省济宁市药品检验所,山东,济宁,272000 |
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| 摘 要： | 目的:为减少抗生素耐药性的产生,寻找适合的抗生素联合用药方式。方法:应用十种常见抗生素分别单独或联合作用于7种常见的致病菌,测定其最低抑菌浓度(MIC)。结果与结论:红霉素对各种致病性球菌有较强的抑菌能力,庆大霉素对各种致病杆菌的作用较强;红霉素或庆大霉素与其它抗生素联用,大多能获得较明显的协同作用,但庆大霉素不宜与青霉素类联合应用。
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| 关 键 词： | 抗生素 致病菌 协同作用 拮抗作用 |
| 文章编号： | 1006-0111(2004)02-0081-02 |
| 收稿时间： | 2003-10-28 |
| 修稿时间： | 2003-10-28 |
The study of the synergy effect of antibiotics in vitro |
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| GUO Jian-qiu and XU Wei-bin. The study of the synergy effect of antibiotics in vitro[J]. The Journal of Pharmaceutical Practice, 2004, 22(2): 81-82 |
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| Authors: | GUO Jian-qiu and XU Wei-bin |
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| Affiliation: | Jining Institute for Drug Control, Jining 272000, China;Jining Institute for Drug Control, Jining 272000, China |
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| Abstract: | Objective: Ques suitable associating medications to reduce the drug tolerance of antibiotics. Methods: Use ten species of common antibiotics alone or synapse to compose with seven species of common bacteria which causing diseases. Results and Conclusion: Erythrocin has a strong inhibition action to pathogenicity coccus. Gentamycin has a strong inhibition action to pathogenicity rods. Most antibiotics have transparent synergistic actions with erythrocin or gentamycin. But gentamycin unite with penicillin is not suitable. |
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| Keywords: | antibiotics the bacteria which causing disease synergistic action antagonistic action |
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