老年非霍奇金淋巴瘤的研究进展

近年来,老年非霍奇金淋巴瘤的发病率不断增高。由于老年人各个系统、器官的功能衰退且常伴有合并疾病,老年非霍奇金淋巴瘤患者与其他非霍奇金淋巴瘤患者在临床特点及治疗、预后方面有所不同。老年非霍奇金淋巴瘤患者的临床表现不明显,易漏诊、误诊;肿瘤预后较差,生存率低;对化疗的耐受差,易发生化疗不良反应。该文旨在探讨老年非霍奇金淋巴瘤的特点及治疗进展,为老年非霍奇金淋巴瘤患者的诊断、治疗提供依据。

Research Progress of Non-Hodgkin Lymphoma in the Elderly

The incidence of non-Hodgkin lymphoma in the elderly continues to increase. Non-Hodgkin lymphoma in the elderly has many differences with other patients in clinical features, treatment and prognosis because of the declining of organ function and accompanied comorbidities in the elderly patients. The clinical manifestations are not obvious in the elderly patients which makes missed diagnosis and misdiagnosis may easily happen;the poor prognosis is poor and the survival rate is low; the tolerance to chemotherapy is poor and side effects of chemotherapy are more likely to occur. Here is to explore the characteristics and treatments of non-Hodgkin lvmDhoma in the elderly oatients, and orovide references for the diagnosis and treatment.