| MicroRNA-21与胃癌关系的研究进展 |
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| 引用本文： | 韩晓娜,唐勇. MicroRNA-21与胃癌关系的研究进展[J]. 医学综述, 2014, 0(14): 2539-2541 |
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| 作者姓名： | 韩晓娜 唐勇 |
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| 作者单位： | 新疆医科大学附属肿瘤医院消化内科,乌鲁木齐830011 |
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| 摘 要： | 胃癌的发生和发展是一个复杂、多步骤的过程,涉及原癌基因和抑癌基因的遗传失调,最近研究较多的微RNA(miRNA)起着重要作用。miRNA是一种长为2123个核苷酸的非编码RNA分子,参与细胞增殖、凋亡和分化以及恶性肿瘤的发生,是重要的调节器。近些年来,人们针对miR-21在恶性肿瘤中的表达研究最为广泛深入,该文就miR-21与胃癌的关系进展予以综述。
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| 关 键 词： | 胃癌 微RNA 微RNA-21 |
The Research Progress of Relationship between MicroRNA-21 and Gastric Cancer |
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| HAN Xiao-na,TANG Yong. The Research Progress of Relationship between MicroRNA-21 and Gastric Cancer[J]. Medical Recapitulate, 2014, 0(14): 2539-2541 |
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| Authors: | HAN Xiao-na TANG Yong |
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| Affiliation: | . ( Digestion Internal Medicine Department, the Third Affiliated Hospital of Xinjiang Medical University, Urumqi 830011, China ) |
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| Abstract: | The genesis and development of gastric cancer is a complex multistep process,involving genetic dysregulation of proto-oncogenes and tummsuppressor genes,and it is revealed by recent studies that the microRNAs play important roles in the process.MicroRNAs are small （approximately 21-23 nucleotides） non-coding RNAs,which are involved in cell proliferation,apoptosis,differentiation,and the onset of malignant tumors as important regulator.In recent yems,miR-21 expression in malignant tumms is the most widely and deeply studied,and here is to make a review of research progress in the relationship between miR-21 and gastric cancer. |
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| Keywords: | Gastric cancer MicroRNA MicroRNA-21 |
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