彩色B超对于海洛因依赖者肝损伤程度的分析

目的探讨彩色B超对于海洛因依赖者肝脏损伤程度的分析。方法选择2011年7月至2012年1月广东佛山市顺德区伍仲佩纪念医院自愿戒毒中心收治的海洛因依赖患者43例作为观察组,另外选取43例健康体检的志愿者作为对照组。利用彩色B超对两组进行肝区检测,观察肝纤维化程度和肝静脉内径的狭窄程度。结果观察组丙氨酸转氨酶、天冬氨酸转氨酶以及抗-HCV阳性率较对照组高(P<0.01)。观察组海洛因依赖者肝脏彩色B超异常率显著高于对照组(60.46%vs 4.65%),差异有统计学意义(P<0.01)。吸食年限>5年的肝功能异常的海洛因依赖者肝纤维化程度显著大于吸食年限≤5年者(P<0.05),且吸食年限>5年的肝功能异常海洛因依赖者肝静脉内径更为狭窄(P<0.05)。静脉注射每日≥2 g的肝功能异常的海洛因依赖者肝纤维化程度显著大于静脉注射每日<2 g者,且静脉注射每日≥2 g的肝功能异常的海洛因依赖者肝静脉内径更为狭窄(P<0.05)。结论利用彩色B超可以诊断出海洛因依赖者不同程度的肝损伤,值得在临床诊疗中推广应用。

Analysis of Color B-mode Ultrasonography on Liver Functional Lesion in Heroin Addicts

Objective To discuss the analysis of liver functional lesion in heroin addicts by using color B-mode uhrasonography. Methods A total of 43 patients from Voluntary Drug Rehabilitation Center of Guangdong Foshan Shunde Wuzhongpei Memorial Hospital during Jul. 2011 and Jan. 2012 were included in the study as observation group, another 43 people who came for physical examination during the same period were included as the control group. Color B-mode ultrasonography was adopted for liver detection, and the degree of hepatic fibrosis and hepatic vein stanosis were observed. Results The ALT, AST and anti-HCV positive rate of the observation group were higher than that of the control group （P 〈 0.01 ）. The abnormal rate of color-B ultrasound liver examination of the observation group was significantly higher than that of the control group （60.46% vs 4.65% ）（ P 〈 0.01 ）. The hepatic fibrosis in heroin addicts with abnormal fiver function with smoking age 〉5 years was significantly higher than those with smoking age ≤5 years（P 〈0.05）, and the vein stenosis was more serious too（ P 〈 0.05 ）. Hepatic fibrosis in heroin addicts with abnormal liver function with intravenous injection of daily ≥2 g was significantly greater than that of intravenous injection of daily 〈 2 g, and the hepatic vein stenosis was more serious too （ P 〈 0.05 ）. Conclusion Color B-mode ultrasonography can diagnose the liver functional lesion in heroin addicts, and is worth spreading and application in clinical.