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生殖相关肾虚证和补肾中药作用机制的研究进展
引用本文:岑妍慧,赵飞兰,范蓉,何国珍. 生殖相关肾虚证和补肾中药作用机制的研究进展[J]. 医学综述, 2014, 0(12): 2226-2228
作者姓名:岑妍慧  赵飞兰  范蓉  何国珍
作者单位:广西中医药大学基础医学院,南宁530001
基金项目:广西教育厅自筹课题(桂教科研[2006]26号);广西中医药大学校级资助课题(200610IJx038);广西中医药大学重大课题(ZDA2012001);广西卫生厅中医药科技专项课题(GZPT12-04)
摘    要:中医认为不孕不育症属于肾虚证,且临床上主要应用补肾中药治疗不孕不育症。大量的实验研究也表明,生殖相关肾虚证存在着下丘脑-垂体-生殖腺轴各器官组织学和分泌功能上的变化,补肾中药可通过调节下丘脑-垂体-生殖腺轴各器官的紊乱而调节和改善生殖功能,对生殖腺轴有多水平、多靶点的调节作用。近年来对生殖相关的肾虚证的本质和补肾中药作用机制的研究已经深入到基因和分子水平。

关 键 词:肾虚证  补肾中药  组织学  功能  下丘脑-垂体-生殖腺轴

Research Progress in the Reproductive-related Kidney Deficiency and Kidney Tonifying Chinese Medicine Mechanism
CEN Yan-hui,ZHAO Fei-lan,FAN Rong,HE Guo-zhen. Research Progress in the Reproductive-related Kidney Deficiency and Kidney Tonifying Chinese Medicine Mechanism[J]. Medical Recapitulate, 2014, 0(12): 2226-2228
Authors:CEN Yan-hui  ZHAO Fei-lan  FAN Rong  HE Guo-zhen
Affiliation:. ( Faculty of Preclinical Medicine of Guangxi University of Chinese Medicine, Nanning 530001, China )
Abstract:Chinese medicine believes that infertility is kidney deficiency syndrome and kidney tonifying Chinese medicines are used to treat infertility in clinical. A large number of experiments have shown that kidney tonifying Chinese medicine can improve and regulate the reproductive function by adjusting morphology and secretory function disorders of hypothalamus-pituitary-gonadal axis organs on multiple levels and at multiple targets. In recent years, the research in reproductive-related kidney essence and kidney tonifying herbs mechanism have gone deep into the genetic and molecular level.
Keywords:Kidney deficiency syndro~me  Kidney toni~ving-Chinese medicine  Histology  Functions  HypothaIamic-pituitary-gonadal axis
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