不同手术方式对子宫肌瘤患者卵巢功能和性功能的影响探讨

目的探究子宫次全切除术和子宫全切术对子宫肌瘤患者卵巢功能及性功能的影响,并为该病的临床治疗提供参考依据。方法选取深圳市龙岗中心医院妇产科于2010年2月至2013年3月收治的90例子宫肌瘤患者,根据患者的治疗意愿进行分组。其中对照组患者采取全子宫切除术,共48例;研究组患者采取次全子宫切除术,共42例。记录两组患者术后卵巢功能及性功能情况,并做对比。结果研究组术前雌二醇水平为(71.6±5.8)U/L,促卵泡生成素为(6.4±0.3)U/L,对照组术前雌二醇水平为(70.9±6.1)U/L,促卵泡生成素为(6.5±0.5)U/L,两组患者术前雌二醇和促卵泡生成素差异无统计学意义(P>0.05);研究组术后雌二醇为(61.3±5.2)U/L,促卵泡生成素为(19.3±1.0)U/L,对照组术后雌二醇为(52.3±4.9)U/L,促卵泡生成素为(12.6±0.8)U/L,研究组雌二醇和促卵泡生成素均高于对照组(P<0.05)。结论子宫次全切除术相较于子宫全切术在保留子宫肌瘤患者的卵巢功能及性功能方面的效果更佳,值得在临床上推广。

Discussion on the Influence of Different Operations on the Ovarian Function and Sexual Function of Patients with Hysteromyoma

Objective To investigate the influence of subtotal hysterectomy and total hysterectomy on the ovarian function and sexual function of patients with hysteromyoma, and provide reference to the clinical treatment of the disease. Methods A total of 90 patients that had hysteromyoma admitted in Longgang Central Hospital from Feb. 2010 to Mar. were divided into the total hysterectomy group（48 cases） and the subtotal hysterectomy group （42 cases） according to the treatment wills of patients. The ovarian function and sexual function of two groups were recorded and compared. Results Before operation, the estradiol level and thefollicle-stimulating hormone （FSH） level of the observation group were （71.6 ± 5.8 ） U/L, （ 6.4 ± 0.3 ） U/L respectively, while those of the control group were（70.9 ± 6.1 ） U/L, （6.5 ± 0.5 ）U/L respectively, and the difference had no statistical significance （P 〉 0.05 ）. After operation ,the estradiol level and the FSH level of observation group were（61.3 ± 5.2 ） U/L, （ 19.3 ± 1.0）U/L respectively and those of the control group were（52.3 ±4. 9） U/L, 12.6 ±0. 8） U/L respectively, the indexes of the observation group were both higher than the control group and the difference had statistical significance（ P 〈 0. 05 ）. Conclusion The clinical effect of subtotal hysterectomy on the ovarian function and sexual function of patients with hysteromyoma is better than the effect of total hysterectomy, so the subtotal hysterectomy is worthy of clinical promotion.