| 急性白血病患者凝血与纤溶指标的变化 |
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| 引用本文： | 罗建伟,李亚红,陈凤如.急性白血病患者凝血与纤溶指标的变化[J].黑龙江医学,2012,36(3):168-169,191. |
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| 作者姓名： | 罗建伟 李亚红 陈凤如 |
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| 作者单位： | 罗建伟 (广东省佛山市顺德区第一人民医院检验科,广东,佛山,528300) ； 李亚红 (广东省佛山市顺德区第一人民医院检验科,广东,佛山,528300) ； 陈凤如 (广东省佛山市顺德区第一人民医院检验科,广东,佛山,528300) ； |
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| 摘 要： | 目的观察急性白血病(AL)患者凝血与纤溶指标的变化,以探索其在急性白血病诊断、治疗及预后判断中的意义。方法采用Sysmex CA-1500全自动血凝仪检测了30例初诊AL患者的血浆凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)、血浆纤维蛋白(原)降解产物(FDPs)、血浆D-二聚体(D-Dimer)及纤维蛋白原定量(FIB),并对其结果进行分析。结果急性白血病组PT、APTT与正常对照组结果无显著性差异(P>0.05),而急性白血病组的FDPs与D-Dimer明显增高,FIB明显降低,与正常对照组比较均有显著差异(P均<0.05)。结论急性白血病患者处于纤溶亢进状态或有出血倾向,FDPs、D-Dimer与FIB的动态监测对急性白血病出血的诊断以及预后判断,有重要的临床意义。
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| 关 键 词： | 急性白血病 血浆纤维蛋白原降解产物 血浆D-二聚体 |
Change of Blood Clotting and Fibrolysis Data for Acute Leukemia |
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| LUO Jian-wei,LI Ya-hong,CHEN Feng-ru.Change of Blood Clotting and Fibrolysis Data for Acute Leukemia[J].Heilongjiang Medical Journal,2012,36(3):168-169,191. |
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| Authors: | LUO Jian-wei LI Ya-hong CHEN Feng-ru |
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| Institution: | (The Lab of the First People′s Hospital of Shunde Distric of Feshan City,Feshan 528300,CHINA) |
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| Abstract: | Objective To observe the BC and fibrolysis of AL patient and discuss the diagnosis,treatment and prognosis.Methods The PT,APTT,FDP,D-Dimer and FIB of 30 cases were detected with Sysmex CA-1500,the results were analyzed.Results The PT and APTT in both group had no difference.The FDP and D-Dimer were increased and FIB decreased in AL group compared with normal P<0.05.Conclusion The AL patient might have tendency of hyperfibrolysis and bleeding.The observing of FDPs、D-Dimer and FIB might obtain diagnosis and predict the prognosis. |
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| Keywords: | Acute Leukemia FDPs D-Dimer |
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