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60例酒精性心肌病心力衰竭患者应用曲美他嗪的疗效分析
引用本文:车琳,张琪,陈晓光.60例酒精性心肌病心力衰竭患者应用曲美他嗪的疗效分析[J].黑龙江医学,2012,36(3):194-195.
作者姓名:车琳  张琪  陈晓光
作者单位:车琳 (黑龙江省医院香坊院区心内科,黑龙江,哈尔滨,150036) ; 张琪 (黑龙江省医院香坊院区心内科,黑龙江,哈尔滨,150036) ; 陈晓光 (黑龙江省医院香坊院区心内科,黑龙江,哈尔滨,150036) ;
摘    要:目的探讨曲美他嗪治疗酒精性心肌病心力衰竭的疗效。方法选取酒精性心肌病心力衰竭患者60例,随机分为对照组和观察组各30例,分别给予常规治疗和加用曲美他嗪治疗2个月,通过6 min步行试验、左室射血分数(LVEF)及C-反应蛋白的含量,来评估曲美他嗪的疗效。结果治疗后,观察组与对照组患者6 min的步行距离(分别为0.5435 km±0.0693 km和0.4927 km±0.0727 km)、LVEF(分别为44.3%±8.6%和49.8%±9.5%)及C-反应蛋白的含量(分别为5.2 mg/L±0.7 mg/L和8.9 mg/L±1.1 mg/L),均优于对照组。结论曲美他嗪通过改善心肌代谢和抗炎作用,改善酒精性心肌病的心功能。

关 键 词:曲美他嗪  酒精性心肌病  心力衰竭

Curative Effect Analysis on Heart Failure of Alcoholic Myocardiopathy Treated with Trimethazine
CHE Lin,ZHANG Qi,CHEN Xiao-guang.Curative Effect Analysis on Heart Failure of Alcoholic Myocardiopathy Treated with Trimethazine[J].Heilongjiang Medical Journal,2012,36(3):194-195.
Authors:CHE Lin  ZHANG Qi  CHEN Xiao-guang
Institution:(Department of Cardiolgy,the Xiangfang Branch of the Provincial Hospital of Heilongjiang, Harbin 150036,CHINA)
Abstract:Objective To discuss the curative effect of heart failure of alcoholic myocardiopathy treated with trimethazine.Methods 60 cases of such patient were divided into test group and control group.The test group was treated with trimethazine on base of routine.6 min walk distance,LVEF and CRP were detected.Results The 6 min walk distance(0.5435±0.0693)km test group and(0.4927±0.0727)km control group,LVEF(44.3±8.6)%in test group and(49.8±9.5)%in control,CRP content was(5.2±0.7)mg/L in test and(8.9±1.1)mg/L in control.The data of test group was better than those in control.Conclusion This drug might improve the heart function with myocardial metabolism and anti inflammation.
Keywords:Trimethazine  Alcoholic myocardiopathy  Heart failure
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