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癌结节在胃癌患者预后中的价值
引用本文:姜惠琴,李倩,李伟,李泓,余一祎,刘天舒.癌结节在胃癌患者预后中的价值[J].临床肿瘤学杂志,2017,22(9):807-811.
作者姓名:姜惠琴  李倩  李伟  李泓  余一祎  刘天舒
作者单位:200032.上海 复旦大学附属中山医院肿瘤内科
摘    要:目的 探讨癌结节在胃癌根治术后患者预后中的价值。方法 收集2015年4月至2016年1月137例胃癌根治术的患者资料,分析癌结节状态与胃癌临床病理特征的关系,并随访患者1年无病生存率。结果 137例胃癌患者的癌结节阳性率为24.8%(34/137)。单因素分析发现,T/N分期越晚、神经/脉管浸润胃癌患者的癌结节阳性率越高。癌结节组与无癌结节组的1年无病生存率分别为59%和85%。对于Ⅰ/Ⅱ期患者,癌结节组和无癌结节组的1年无病生存率分别为40%和91%。结论 胃癌根治术后患者的癌结节与分期、神经/脉管浸润呈正相关。癌结节阳性提示胃癌术后高复发风险,其预后价值在Ⅰ/Ⅱ期胃癌中更显著。

关 键 词:胃癌  癌结节  预后
收稿时间:2017-04-13
修稿时间:2017-08-08

Prognostic value of tumor deposit in gastric cancer patients
JIANG Huiqin,LI Qian,LI Wei,LI Hong,YU Yiyi,LIU Tianshu.Prognostic value of tumor deposit in gastric cancer patients[J].Chinese Clinical Oncology,2017,22(9):807-811.
Authors:JIANG Huiqin  LI Qian  LI Wei  LI Hong  YU Yiyi  LIU Tianshu
Institution:Department of Medical Oncology, Zhongshan Hospital, Fudan University, Shanghai 200032,China
Abstract:Objective To examine the prognostic values of tumor deposits (TDs) in gastric cancer.Methods The patients underwent radical gastrectomy and histopathologically diagnosed as gastric cancer from April 2015 to January 2016 were involved.The relationship between the status of TDs and clinicopathological features of gastric cancer was analyzed.The 1-year disease-free survival (DFS) rate was calculated.Results The positive rate of TDs in 137 cases of gastric cancer was 24.8%.Univariate analysis showed that T/N stage and neural/vascular invasion were related to the positive expression of TDs.The 1-year DFS rates of the TD positive group and TD negative group were 59% and 85%,respectively.In the Ⅰ /Ⅱ stage,the 1-year DFS rates of the TD positive group and TD negative group were 40% and 91%,respectively.Conclusion The TD status was positively correlated with T/N stage and nerve/vascular invasion after radical gastrectomy.TD positive was a poor prognostic factor,indicatingearly relapse after radical gastrectomy.The prognostic value of TD was more significant in stage Ⅰ / Ⅱ gastric cancer patients.
Keywords:Gastric cancer  Tumor deposit (TD)  Prognosis
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