| 运动训练对肾上腺神经生长因子表达的影响 |
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| 引用本文： | 李江丽,王航平,王廷华.运动训练对肾上腺神经生长因子表达的影响[J].四川解剖学杂志,2012,20(1):12-14. |
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| 作者姓名： | 李江丽 王航平 王廷华 |
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| 作者单位： | 1. 昆明医学院神经科学研究所,昆明,650031
2. 云南师范大学体育学院,昆明,650000 |
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| 摘 要： | 目的调查长期游泳训练对大鼠肾上腺(NGF)表达的影响。方法成年SD大鼠分为无负重组,轻负重组(体重的1%),中负重组(3%)和中负重组(5%)四组。用水槽进行长期游泳训练6周,每天1h。6周后取肾上腺用RT-PCR检测NGF水平。结果各组肾上腺均能检测到NGF mRNA,中度负重组肾上腺NGF表达水平明显下调,与其它两组比差异有统计学意义(P<0.05)。结论重度负重游泳导致肾上腺NGF表达下调,提示NGF在长期游泳训练对大鼠肾上腺可能有其生物学作用。
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| 关 键 词： | 神经生长因子 游泳 肾上腺 大鼠 |
Effect of Loaded-swimming on the Expression of Nerve Growth Factor mRNA in Adrenal Body of Rats |
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| Li Jiangli
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Wang Hangping
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Wang Tinghua.Effect of Loaded-swimming on the Expression of Nerve Growth Factor mRNA in Adrenal Body of Rats[J].Sichuan Journal of Anatomy,2012,20(1):12-14. |
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| Authors: | Li Jiangli Wang Hangping Wang Tinghua |
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| Institution: | 1(Institute of Neuroscience,Kunming medical college,Kunming 650031,China) 2(School of Physical Education of Yunnan Normal University,Kunming 650000,China) |
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| Abstract: | Objective To investigate the effect of different loaded-swimming on the expression nerve growth factor(NGF) mRNA in adrenal body in rats.Methods Rats were divided into control group,light,middle and heavy weight loaded-swimming groups respectively.All rats were trained in swimming pool for 1h each day till 6 weeks.the adrenal body was collected and NGF mRNA expression was detected by RT-PCR.Results Level of NGF mRNA expression was downregulated in heavy weight loading group of rats experienced 6 weeks swimming training.Conclusion The present study suggested NGF was involved in the process of swimming,which is related to the endocrine regulation in adrenal body after loaded-swimming. |
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| Keywords: | Nerve growth factor(NGF) Swimming Adrenal body Rats |
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