中药调节噪声引起的动物肝AST、ALT变化的研究

以大鼠为实验对象，研究了在不同声强，不同时间暴露下的大鼠肝中天冬氨酸转氨酶（AST）和丙氨酸转氨酶（ALT）活性的变化。实验结果表明，噪声组大鼠肝AST和ALT活性指标均低于正常值，说明噪声对大鼠肝能造成一定的损害，在噪声环境中，将注射一定剂理黄芪或红景天提取液的大鼠与未注射的大鼠各测试指标进行比较，发现两种药物对噪声刺激产生的损害都有一定的防治作用。

Effects of Chinese herbal medicine on adjusting changes in activities of AST and ALT in the rat liver caused by noise

Objectives To study the effects of Chinese herbal medicine on adjusting changes in activities of AST and ALT in the liver of rats exposed to noise with varied intensity and length.Methods One hundred and fifty rats were divided into six groups,including one control group,one exposed group without treatment of Chinese herbal medicine,and four groups exposed to noise with varied intensity and length and treated with Chinese herbal medicine,Huangqi(Astragalus)or Hongjingtian(Rhodiola).Activities of AST and ALT were measured for the liver of rats exposed to noise with and without treatment of Chinese herbal medicine.Results Activities of AST and ALT in the exposed group were lower than those in the control group.And,activities of AST and ALT increased in the exposed groups treated with Huangqi(Astragalus)or Hongjingtian(Rhodiola),indicating interference of noise could be protected by them. Conclusions Injury caused by noise could be prevented by Chinese herbal medicine,Huangqi and Hongjingtian.