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Ampicillin in breast milk during puerperal infections |
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| Authors: | I. Matheson M. Samseth H. A. Sande |
| Affiliation: | (1) Department of Pharmacotherapeutics and Pharmacy, University of Oslo, Oslo, Norway;(2) Department of Division of Microbiology, University of Oslo, Oslo, Norway;(3) Department of Gynecology and Obstetrics, Ullevål Hospital, Oslo, Norway |
| Abstract: | Summary Low concentrations of ampicillin were found in colostrum/breast milk from 6 mothers treated with pivampicillin 1.05 to 2.1 g daily during the first to eighth day postpartum in the maternity ward. It was calculated that the breast-fed infant could theoretically receive 0.05–0.37% of the dose/kg given to the mother. It is concluded that direct exposure of the breast-fed infant suckling from a mother under treatment with ampicillin or pivampicillin seems to be minimal. |
| Keywords: | pivampicillin ampicillin breast milk puerperal infection |
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