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Cellulose tris(3,5-dichlorophenylcarbamate) immobilised on silica: a novel chiral stationary phase for resolution of enantiomers
Authors:Zhang Tong  Nguyen Dung  Franco Pilar  Isobe Yutaka  Michishita Takashi  Murakami Tatsushi
Affiliation:

aChiral Technologies Europe, Parc d’Innovation, Bd. Gonthier d’Andernach, 67404 Illkirch Cedex, France

bDaicel Chemical Industries Ltd., CPI Company, Arai Plant, Myoko-City, Niigata 944-8550, Japan

Abstract:CHIRALPAK IC is a new chiral stationary phase (CSP) made by immobilising cellulose tris(3,5-dichlorophenylcarbamate) on silica gel. The chiral selector is distinct from any other commercially available polysaccharide-based CSPs. Apart from its compatibility with the whole series of solvents; this CSP is able to operate under various chromatographic conditions and bring about new characteristics in enantiomeric recognition. It can afford many large and specific enantiomeric separations. It exhibits complementary properties with regard to the existing immobilised chiral packing materials of the same category.
Keywords:CHIRALPAK IC   Cellulose tris(3,5-dichlorophenylcarbamate)   Immobilised polysaccharide-based chiral stationary phases   Enantiomeric resolution by liquid chromatography
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