肝干细胞的研究进展及应用前景

目的阐述肝干细胞（liver stem cell，LSC）的研究进展并展望其应用前景。方法广泛查阅近年来相关文献，根据研究成果，综述LSC研究的最新进展。结果LSC向特定的细胞分化和增殖受多种因素影响。LSC活化、分离培养、筛选及鉴定等方法尚未成熟。结论随着研究不断地深入，LSC有望成为肝病治疗的新型种子细胞，但其研究有待进一步完善。

DEVELOPMENT OF RESEARCH ON LIVER STEM CELL AND ITS FUTURE APPLICATION

OBJECTIVE: To investigate the research development of the liver stem cell (LSC) and to predict its future application. METHODS: Based on our own researches and combined with the review of the related literature at home and abroad, we analyzed and evaluated the latest development of the research on the LSC. RESULTS: We knew the differentiation and proliferation of the LSC towards some kinds of specified cells were affected by many factors; and the researches on the LSC in regard to its activation, isolating culture, bolting, and evaluation still needed further improvements. CONCLUSION: With the development of the research, the liver stem cell can become a new seed cell to cure some liver diseases.