青少年开角型青光眼118例临床分析

目的:探讨青少年开角型青光眼的临床特点,并对其早期诊断、治疗、预后进行分析讨论。方法:抽取1997/2007年收治的青少年开角型青光眼118例(236眼),对其性别、年龄、屈光状态眼压、房角、眼底、视野、家族史等各有关参数及治疗情况等,进行回顾性统计分析。结果:男51例(43.2%)、女67例(56.8%),发病年龄10~20岁占本组病例的70.3%,并发近视眼者占77.1%(182/236),治疗前最高眼压10~21mmHg者80眼(33.9%),21~25mmHg者52眼(22.0%),26~30mmHg者64眼(27.1%),31~40mmHg者29眼(12.3%),>40mmHg者11眼(4.7%)。C/D<0.6者146眼(61.9%),C/D0.6~0.8者81眼(34.3%),C/D>0.8者9眼(3.8%)。视网膜神经纤维层缺损阳性率为94.9%,视野缺损阳性率为65.2%。房角全部为开角未见特殊异常。有青光眼家庭史者13例(11.0%)。本组有28例(50眼)施行滤过性手术,其余均为药物保守治疗。治疗后眼压控制良好,但视力提高者仅57眼(24.2%)。结论:青少年开角型青光眼(juvenile open angle glaucoma,JOAG)的发病年龄越来越年轻化,近视眼是JOAG最主要危险因素之一,视网膜神经纤维层缺损是JOAG早期诊断的一个高敏感性和高特异性客观依据,JOAG应早期诊断、合理治疗、定期随访,其预后比较乐观。

Clinical analysis of 118 juvenile open-angle glaucoma cases

AIM:To evaluate the clinical appearances,early diagnosis,treatment and prognosis of juvenile open-angle glaucoma(JOAG).METHODS:The clinical retrospective analysis compared gender,age,refraction,intraocular pressure(IOP),angle of anterior,ocular fundus,visual field,family history and treatment was conducted on 118 cases(236 eyes)with JOAG from 1997 to 2007.RESULTS:In all cases,51 cases(43.2%)were male and 67 cases(56.8%)were female.The age from 10 to 20 years old in this group were covered 70.3%.Those associ...