肺炎链球菌对大环内酯类抗生素耐药性检测

[目的]了解我地区肺炎链球菌临床分离株对大环内酯类药物的耐药的状况。[方法]从我院各类临床标本中分离的98株肺炎链球菌进行青霉素，红霉素等大环内酯类药物K—B纸片扩散法药物敏感试验。[结果]98株肺炎链球菌青霉素敏感率100％，红霉素的耐药率高达86．7％，其中cMLS型占88．2％，iMLS型占7．1％，M型占4．7％。[结论]我地区分离肺炎链球菌感染应在药物敏感试验的指导下，合理应用大环内酯类抗生素。

DETECTION OF RESISTANCE OF STREPTOCOCCUS PNEUMONIAE TO MACROLIDS

[ Objective ] To investigate the resistance of clinical isolates of Streptococcus pneumoniae to macrolids in our county. [ Methods] The drug - sensitive test was performed for 98 strains of Streptococcus pneumoniae isolated in our hospital with the K - B strip expansion method. [Results] The sensitive rate of the 98 strains was 100% and 86.7% to penicillin and erythromycin, respectively. The cMLS type was found in 88.2% , iMLS type in 7.1% and M type in 4.7%. [ Conclusion] The clinical use of macrolids should be guided by results of drug - sensitive tests.