不同浓度舒芬太尼联合腹横肌平面阻滞对剖宫产术后镇痛的效果研究

目的:探讨不同浓度舒芬太尼联合腹横肌平面阻滞对剖宫产术后镇痛的效果。方法:选取广州中医药大学深圳医院（福田）2020年1月至2021年6月择期在椎管内麻醉下行剖宫产手术的产妇共150例，年龄21～35岁，身高151～169 cm，体质量54～75 kg，美国麻醉医师协会（ASA）分级Ⅰ或Ⅱ级，采用随机数字表法将其分为A...

Analgesia effect of different concentrations of sulfentanyl combined with transversus abdominis plane block after cesarean section

Objective　To investigate theanalgesia effect of different concentrations of sulfentanyl combined withtransverse abdominis plane block after cesarean section. Methods　A total of 150 womentaking elective cesarean section under intravertebral anesthesia in ShenzhenHospital (Futian), Guangzhou University of Traditional Chinese Medicine betweenJanuary 2020 and June 2021 were selected, and they were 21-35 years old and151-169 cm tall and of American Society of Anesthesiologists (ASA) Ⅰ or Ⅱ and weighed 54-75 kg. They were divided into group A, group B, andgroup C by the random number table method, taking patient controlledintravenous analgesia with 0.25, 0.50, 1.00 μg/ml sulfentanyl respectively andultrasound-guided transverse muscle plane block. The Visual Analogue Scale(VAS) scores 2, 4, 8, 12, 24, and 48 h after cesarean section were observed andrecorded. How many times the pumps had been pressed and sulfentanyl usagewithin 48 h were recorded. The incidences of dizziness, nausea and vomiting,skin pruritus, no exhaust, and complications of transverse abdominis planeblock after were recorded. Statistics were performed using statistical methodssuch as one-way ANOVA and chi-square test. Results　There were no statistical differences in thenumber the pumps had been used and the total sulfentanyl volume between thethree groups (all P>0.05). Thesulfentanyl usage was (17.59±3.65) μg in group A, was (33.35±6.30) μg in groupB, and was (65.39±6.98) μg in group C (F=123.24, P<0.001). There were nostatistical difference in the VAS scores at different time points between thethree groups (all P>0.05). Theincidence of no exhaust was 6.2% (3/48) in group A, 8.5% (4/47) in group B, and22.4% (11/49) in group C, with the highest in group C (χ²=6.951, P=0.031)and no statistical difference between group A and group B. Conclusion　After transverseabdominis plane block, patient controlled intravenous analgesia with 0.25~0.50μg/ml sulfentanyl is effective, with a low incidence of adverse reactions.