基于前馈控制的肠内营养支持联合每日唤醒在机械通气患者中应用效果分析

目的　探讨机械通气患者应用基于前馈控制的肠内营养支持联合每日唤醒的效果分析。方法　选取2019年11月至2020年11月在无锡市第二人民医院进行机械通气治疗的80例患者，采用随机数字法将其分为对照组和试验组，每组40例。对照组男26例，女14例，年龄（46.35±2.37）岁；试验组男28例，女12例，年龄（48.26±3.16）岁。对照组给予常规护理干预，试验组给予基于前馈控制的肠内营养支持联合每日唤醒。对比两组患者的营养状态、对肠内营养耐受程度、镇静治疗时间、机械通气时间及ICU住院时间。统计学方法采用独立样本t检验、χ²检验。结果　与对照组相比，试验组患者的血清白蛋白、前白蛋白、血红蛋白水平分别为（38.97±7.16）g/L、（258.57±23.48）mg/L、（134.67±14.37）g/L，均显著优于对照组（均P<0.05）；试验组患者对肠内营养耐受较差的发生率显著低于对照组［2.5%（1/40）比27.5%（11/40）］，两组比较差异有统计学意义（χ²=9.804，P=0.002）；试验组患者的镇静治疗时间、机械通气时间、ICU住院时间分别为（4.68±2.67）d、（6.16±3.49）d、（6.94±4.67）d，均显著少于对照组（均P<0.05）。结论　在机械通气患者中应用基于前馈控制的肠内营养支持联合每日唤醒，保证其治疗期间机体充足的营养供应，减少谵妄的发生，促进疾病快速康复。

Feedforward-controlled enteral nutrition support combined with daily arousal for patients undergoing mechanical ventilation

Objective　To investigate the effect of feedforward-controlled enteral nutrition support combined with daily arousal for patients undergoing mechanical ventilation. Methods　From September 2019 to September 2020, 80 patients treated by mechanical ventilation in Wuxi Second People's Hospital were selected, and were divided into a control group and an experimental group by the random number table method, with 40 cases in each group. The control group had 26 males and 14 females, and were (46.35±2.37) years old. The experimental group had 28 males and 12 females, and were (48.26±3.16) years old. Routine nursing intervention was given to the control group, and the experimental group was given enteral nutrition support based on feedforward control and daily arousal. The nutritional status, the degrees of enteral nutrition tolerance, sedation treatment times, mechanical ventilation times, and ICU hospitalization times were compared between the two groups. Independent-Sample t and χ² tests were applied. Results　The levels of albumin, prealbumin, and hemoglobin were (38.97±7.16) g/L, (258.57±23.48) mg/L, and (134.67±14.37) g/L in the experimental group, which were significantly higher than those in the control group (all P<0.05). The incidence of poor enteral nutrition intolerance in the experimental group was significantly lower than that in the control group 2.5% (1/40) vs. 27.5% (11/40); χ²=9.804， P=0.002]. The sedation time, mechanical ventilation time, and ICU stay in the experimental group were (4.68±2.67) days, (6.16±3.49) days, and (6.94±4.67) days, which were significantly less than those in the control group (all P<0.05). Conclusion　Feedforward controlled enteral nutrition support combined with daily arousal for patients taking mechanical ventilation can ensure adequate nutrition, reduce the occurrence of delirium, and promote their recovery.