脓毒症相关生物标志物及作用机制研究进展

脓毒症是临床中常见的一种危重症感染导致的多器官功能障碍综合征，也是临床中常见的患者死亡的主要原因之一，具有高发病率、高病死率的特点，尽管现在抗生素利用和生命支持方面有了很大的改善，但是脓毒症患者病死率仍居高不下，早期识别脓毒症生物标志物变化，对脓毒症治疗提供思路、判断患者预后有很大益处。

Research progress of sepsis-related biomarkers and mechanisms of action

Sepsis is a common clinical syndrome of multiple organ dysfunction caused by a critical infection, and is one of the major clinical causes of patients' death, with a high morbidity and mortality. Despite significant improvements in antibiotic use and life support, the mortality in patients with sepsis is still high. Early identification of biomarker changes in sepsis is of great benefit in providing ideas for the treatment of sepsis and determining the prognosis of patients.