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抑郁障碍自杀与细胞因子的关系研究进展
引用本文:李仙,李建琼,曾淑娥,侯亚婷,杨皓琪,杨蜀云,季长亮.抑郁障碍自杀与细胞因子的关系研究进展[J].临床精神医学杂志,2022(1):75-77.
作者姓名:李仙  李建琼  曾淑娥  侯亚婷  杨皓琪  杨蜀云  季长亮
作者单位:云南省精神病医院;云南省迪庆藏族自治州人民医院
基金项目:云南省教育厅科学研究基金项目(2018JS247)。
摘    要:自杀不仅仅是抑郁障碍最严重的后果,更是全社会关注的公共卫生问题,约4%的抑郁障碍患者死于自杀.目前很多研究发现抑郁障碍自杀与5-羟色胺系统、下丘脑-垂体-肾上腺(HPA)轴、神经营养因子和细胞因子等生物学标记物有关.如何准确预测抑郁障碍患者的自杀风险是目前多项研究的热点,本文就抑郁障碍自杀与细胞因子的关系进行综述.

关 键 词:抑郁障碍  自杀  细胞因子

Research development on the relation between suicide and cytokines in major depressive disorder
LI Xian,LI Jian-qiong,ZENG Shu-e,HOU Ya-ting,YANG Hao-qi,YANG Shu-yun,JI Chang-liang.Research development on the relation between suicide and cytokines in major depressive disorder[J].Journal of Clinical Psychological Medicine,2022(1):75-77.
Authors:LI Xian  LI Jian-qiong  ZENG Shu-e  HOU Ya-ting  YANG Hao-qi  YANG Shu-yun  JI Chang-liang
Institution:(Yunnan Psychiatric Hospital,Kunming 650224,China)
Abstract:Suicide is the most severe result of major depressive disorder and a public health problem of wide concern,with 4%of patients with major depressive disorder committing suicide.Recent study shows suicide in major depressive disorder links to 5-hydroxytryptamine system,hypothalamic-pituitary-adrenal(HPA)axis,neurotrophic factors and cytokines.As the prognosis of the suicide risk of patients with major depressive disorder is a hot topic of various studies,this paper tries to illustrate the relation between suicide and cytokines in major depressive disorder.
Keywords:major depressive disorder  suicide  cytokines
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