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CD36 palmitoylation disrupts free fatty acid metabolism and promotes tissue inflammation in non-alcoholic steatohepatitis
Authors:Lei Zhao  Chang Zhang  Xiaoxiao Luo  Pei Wang  Wei Zhou  Shan Zhong  Yunxia Xie  Yibo Jiang  Ping Yang  Renkuang Tang  Qin Pan  Andrew R. Hall  Tu Vinh Luong  Jiangao Fan  Zac Varghese  John F. Moorhead  Massimo Pinzani  Yaxi Chen  Xiong Z. Ruan
Affiliation:1. Centre for Lipid Research & Key Laboratory of Molecular Biology for Infectious Diseases (Ministry of Education), Institute for Viral Hepatitis, Department of Infectious Diseases, The Second Affiliated Hospital, Chongqing Medical University, 400016 Chongqing, China;2. The Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases (CCID), Zhejiang University, 310058 Hangzhou, China;3. Astra Zeneca-Shenzhen University Joint Institute of Nephrology, Centre for Nephrology, Shenzhen University Medical School, Shenzhen University, Shenzhen, China;4. Department of Gastroenterology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, 200092 Shanghai, China;5. Sheila Sherlock Liver Centre, Royal Free London NHS Foundation Trust and UCL Institute for Liver and Digestive Health, University College London Medical School, Royal Free Campus, University College London, London NW3 2PF, United Kingdom;6. Department of Cellular Pathology, Royal Free London NHS Foundation Trust, London, UK;7. John Moorhead Research Laboratory, Centre for Nephrology, University College London Medical School, Royal Free Campus, University College London, London NW3 2PF, United Kingdom
Abstract:
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  • Keywords:Fatty acid translocase CD36  Non-alcoholic steatohepatitis  Fatty acid metabolism  Palmitoylation
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