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A simple diet- and chemical-induced murine NASH model with rapid progression of steatohepatitis,fibrosis and liver cancer
Authors:Takuma Tsuchida  Youngmin A. Lee  Naoto Fujiwara  Maria Ybanez  Brittany Allen  Sebastiao Martins  M. Isabel Fiel  Nicolas Goossens  Hsin-I. Chou  Yujin Hoshida  Scott L. Friedman
Affiliation:1. Division of Liver Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, USA;2. Research Division, Mitsubishi Tanabe Pharma Corporation, Saitama, Japan;3. Department of Pathology, Icahn School of Medicine at Mount Sinai, New York, USA;4. Departamento de Patologia, Faculdade de Medicina FMUSP, Universidade de São Paulo, São Paulo, SP, Brazil
Abstract:
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  • Keywords:NAFLD  NASH  Steatohepatitis  Fatty liver disease models  Hepatic stellate cells  Fibrosis  Hepatocellular carcinoma  Insulin resistance
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