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知杞冲剂对成人牙周炎疗效的评价
引用本文:陈铁,黄世光,王华东,谢敏,马淑媛,李巧香.知杞冲剂对成人牙周炎疗效的评价[J].中国病理生理杂志,2003,19(5):679-681.
作者姓名:陈铁  黄世光  王华东  谢敏  马淑媛  李巧香
作者单位:1. 暨南大学医学院口腔医学系, 广东 广州 510632;
2. 暨南大学医学院病理生理学教研室, 广东 广州 510632;
3. 暨南大学医学院第一附属医院口腔科, 广东 广州 510632;
4. 湖南省中医院, 湖南 长沙 415300
摘    要:目的:观察知杞冲剂对成人牙周炎的辅助治疗效果。方法:对100例成人牙周炎患者先行龈上洁治、龈下刮治术,然后随机分为两组,对照组32例采用甲硝唑口服治疗;试验组68例采用知杞冲剂口服治疗。分别观察治疗前后疼痛反应、出血指数、菌斑指数、探诊深度、牙周袋内微生物变化及不良反应等,观察期为30d。结果:知杞冲剂对成人牙周炎的显效率明显高于甲硝唑治疗组(P<0.05);出血指数、菌斑指数和探诊深度均显著低于对照组(P<0.05)。结论:知杞冲剂能有效改善牙周状况,对成人牙周炎有显著辅助治疗效果;知杞冲剂药源充足,制备简便,无毒副作用,具有临床推广价值。

关 键 词:牙周炎  甲硝唑  知杞冲剂  
文章编号:1000-4718(2003)05-0679-03
收稿时间:2002-03-07

Effect of Zhiqi oral solution on adult periodontitis
CHEN Tie ,HUANG Shi-guang ,WANG Hua-dong ,XIE Min ,MA Shu-yuan ,LI Qiao-xiang.Effect of Zhiqi oral solution on adult periodontitis[J].Chinese Journal of Pathophysiology,2003,19(5):679-681.
Authors:CHEN Tie  HUANG Shi-guang  WANG Hua-dong  XIE Min  MA Shu-yuan  LI Qiao-xiang
Institution:1. Department of Conservative Dentistry, Jinan University, Guangzhou 510632, China;
2. Department of Pathophysiology, Jinan University, Guangzhou 510632, China;
3. Department of Conservative Dentistry, The First Affiliated Hospital, Medical College of Jinan University, Guangzhou 510632, China;
4. Tranditonal Chinese Medical Hospital of Hunan Province, Changsha 415300, China
Abstract:AIM:To evaluate therapeutic effect of Zhiqi oral solution on adult periodontitis. METHODS: Supragingival scaling and root planning were carried out in 100 patients with adult periodontitis. Then the patients with periodontitis were divided into two groups randomly. 32 patients in the control group took orally Metronidazole and 68 patients in the experimental group took orally Zhiqi oral solution. The pain reaction, bleeding index, probing depth, plaque index, changes of microorganisms in periodontal pocket and side effect before and after the treatment were observed at a 30 days observation period. RESULTS:Zhiqi oral solution had a therapeutic effect on periodontitis, compared with the control group ( P< 0.05). The bleeding index and plaque index in patients of two groups were improved obviously compared with before treatment ( P< 0.05). However Zhiqi oral solution had an obvious effect on decreasing the probing depth( P< 0.05).CONCLUSION:Zhiqi oral solution improves effectively the condition of periodontium, and its supplementary treatment effect on adult periodontitis is obvious.
Keywords:Periodontitis  Metronidazole  Zhiqi oral solution
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