First human case of co-infection with two different subtypes of hepatitis e virus |
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Authors: | Moal Valérie Gerolami René Colson Philippe |
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Affiliation: | Centre de Néphrologie et Transplantation Rénale, H?pital Conception, Assistance Publique des H?pitaux de Marseille, Aix-Marseille Université, Marseille, France. |
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Abstract: | Hepatitis E virus (HEV), the main etiologic agent of enterically transmitted acute hepatitis in developing countries, is now recognized as an emerging agent of autochthonous disease and chronic hepatitis E in immunocompromised patients in Europe where HEV infection is probably zoonotically acquired. We describe the first human case of acute HEV infection with two genotype 3 viruses in a French kidney transplant recipient, probably acquired through consumption of uncooked pig liver sausage (figatellu). The patient presented two viral sequences nearly identical to sequences recovered from figatelli. Autochthonous co-infections with different genotype 3 HEV strains can occur in our geographical area. |
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