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| 乳腺浸润性导管癌超声表现与病理及Id2、Id3mRNA表达关系的研究 | |
| 引用本文： | 郑敏,穆丹梅,戴险峰,郑淼,魏晓冬,刘磊,杨木蕾.乳腺浸润性导管癌超声表现与病理及Id2、Id3mRNA表达关系的研究[J].中国医学影像技术,2009,25(2):202-206. |
| 作者姓名： | 郑敏 穆丹梅 戴险峰 郑淼 魏晓冬 刘磊 杨木蕾 |
| 作者单位： | 1. 哈尔滨医科大学第一临床医院超声科,黑龙江,哈尔滨,150001 2. 哈尔滨医科大学第一临床医院超声科,黑龙江,哈尔滨,150001;大庆油田总医院B超室,黑龙江,大庆,163001 3. 大庆油田总医院磁共振室,黑龙江,大庆,163001 |
| 基金项目： | 黑龙江省自然科学基金重点项目 |
| 摘 要： | 目的 对照分析乳腺浸润性导管癌超声表现与病理改变的关系;尝试探讨Id2mRNA及Id3mRNA表达与IDC超声表现之间的关系.方法 应用实时荧光定量RT-PCR检测36例IDC样本中Id2mRNA及Id3mRNA的表达,并与IDC超声表现对照分析.结果 Id2mRNA在正常组织中表达高于癌组织(P＜0.05),WHOⅢ级表达低于WHOⅠ级(P＜0.05);Id3mRNA的表达相反(分别为P＜0.01,P＜0.05).Id2mRNA的表达与IDC超声征象之间无显著性意义(P均＞0.05).毛刺征及周边导管扩张组Id3mRNA均呈高表达(P均＜0.01).结论 IDC声像图表现与病理组织学变化密切相关.IDC的二维超声征象可在一定程度上反应Id3mRNA的表达水平. |
| 关 键 词： | 乳腺肿瘤 超声检查 病理组织学 Id基因 逆转录聚合酶链反应 |
| 收稿时间： | 3/6/2008 12:00:00 AM |
| 修稿时间： | 2008/6/30 0:00:00 |
Ultrasonic appearance in breast infiltrating ductal carcinoma, pathology and the expression of Id2mRNA and Id3mRNA |
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| ZHENG Min,MU Dan-mei,DAI Xian-feng,ZHENG Miao,WEI Xiao-dong,LIU Lei and YANG Mu-lei.Ultrasonic appearance in breast infiltrating ductal carcinoma, pathology and the expression of Id2mRNA and Id3mRNA[J].Chinese Journal of Medical Imaging Technology,2009,25(2):202-206. | |
| Authors: | ZHENG Min MU Dan-mei DAI Xian-feng ZHENG Miao WEI Xiao-dong LIU Lei and YANG Mu-lei |
| Institution: | B-type Ultrasound Room,;Department of Magnetic Resonance, Daqing Oilfield General Hospital, Daqing 163001, China;Department of Ultrasound, the First Clinical College of Harbin Medical University, Harbin 150001, China;Department of Ultrasound, the First Clinical College of Harbin Medical University, Harbin 150001, China; Department of Magnetic Resonance, Daqing Oilfield General Hospital, Daqing 163001, China;Department of Magnetic Resonance, Daqing Oilfield General Hospital, Daqing 163001, China;Department of Ultrasound, the First Clinical College of Harbin Medical University, Harbin 150001, China;Department of Ultrasound, the First Clinical College of Harbin Medical University, Harbin 150001, China;Department of Ultrasound, the First Clinical College of Harbin Medical University, Harbin 150001, China;Department of Ultrasound, the First Clinical College of Harbin Medical University, Harbin 150001, China |
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