| 抗胸腺细胞球蛋白治疗肾移植术后早期耐激素的排斥反应 |
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| 引用本文： | 王书龙,张艮甫,黄赤兵,范明齐,刘峰. 抗胸腺细胞球蛋白治疗肾移植术后早期耐激素的排斥反应[J]. 中国现代医学杂志, 2003, 13(19): 41-43 |
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| 作者姓名： | 王书龙 张艮甫 黄赤兵 范明齐 刘峰 |
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| 作者单位： | 第三军医大学附属新桥医院肾移植科,重庆,400037 |
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| 摘 要： | 目的：观察抗胸腺细胞球蛋白(ATG)治疗肾移植术后早期耐激素排斥反应的效果。方法：对34例尸体肾移植术后3d内应用激素冲击治疗期间发生排斥反应的患者以及手术3d后发生耐激素排斥反应的患者采用ATG治疗。结果：其中32例排斥反应得以逆转，肾功能恢复正常，其治愈率为94．1％。2例虽然控制排斥反应，但其肾功能未能恢复，未行移植肾切除。结论：抗胸腺细胞球蛋白(ATG)治疗早期耐激素排斥反应的效果显著，可以使有耐激素排斥反应的肾移植患者获得良好的肾功能。
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| 关 键 词： | 肾移植 耐激素排斥反应 抗胸腺细胞球蛋白 |
Treament of Early Steroid-Resistant Rejection with Antithymocyte Globulin After Kidney Transplantation |
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| Wang Shulong,Zhang. Yinpu,Huang Chibing,et al.. Treament of Early Steroid-Resistant Rejection with Antithymocyte Globulin After Kidney Transplantation[J]. China Journal of Modern Medicine, 2003, 13(19): 41-43 |
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| Authors: | Wang Shulong Zhang. Yinpu Huang Chibing et al. |
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| Affiliation: | Wang Shulong,Zhang. Yinpu,Huang Chibing,et al.Department of Kidney Transplantation,Xinqiao Hospital,The Third MilitaryMedical University,Chongqing 400037 |
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| Abstract: | Objective:To observe the effect of antithymocyte globulin( ATG) on early steroid - resistant rejections after kidney transplantation. Methods:34 steroid - resistant patients were treated with ATG who had rejection during hormone impact treatment within 3 days after transplantation or resistant response 3 days after kidney transplantation. Results: In 32 of 34 steroid - resistant patients after kidney transplantation, their rejections were reversed and their renal function recovered with curing rate of 94.1 %. In 2 of 43 cases, their rejections were controlled, but their renal function did not recover. Conclusions: ATG was a potent immunosuppresant capable of reversing early steroid - resistant rejections. Patients with steroid - ressitant rejectons after transplantation could get favorable renal function. |
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| Keywords: | Renal Transplantation Steroid - resistant Rejection Antithymocyte Globulin |
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