| 细胞角蛋白8与肿瘤 |
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| 引用本文： | 姚景辉.细胞角蛋白8与肿瘤[J].国际肿瘤学杂志,2010,37(12). |
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| 作者姓名： | 姚景辉 |
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| 作者单位： | 安徽省铜陵市人民医院肿瘤一科,244009 |
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| 摘 要： | 细胞角蛋白8(CK8)是一种中间丝蛋白,属于细胞骨架蛋白家族.研究表明,CK8表达或翻译后修饰异常将影响其活性,是相关肿瘤发生发展的重要原因之一.对CK8在肿瘤发生发展中作用的深入研究,可以为肿瘤的预防及治疗提供帮助.
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| 关 键 词： | 角蛋白质类 蛋白质加工 转译后 肿瘤 肿瘤转移 |
Cytokeratin 8 and cancer |
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| YAO Jing-hui.Cytokeratin 8 and cancer[J].Journal of International Oncology,2010,37(12). |
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| Authors: | YAO Jing-hui |
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| Abstract: | Cytokeratin 8 ( CK8 ) belongs to the keratin family of intermediate filament cytoskeletal proteins. A lot of researches have demonstrated that abnormal expression or post-translational modifications of CK8 may affect its activity and consequently affect the development and progression of tumors. Therefore, investigating the role of CK8 in tumorigenesis may contribute to the prevention and treatment of tumors. |
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| Keywords: | Keratins Protein processing post-translational Neoplasms Neoplasm metastasis |
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