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肾细胞癌尿激酶型纤溶酶原激活物表达的研究
引用本文:卓栋,姜书传,韩杰,程庆水. 肾细胞癌尿激酶型纤溶酶原激活物表达的研究[J]. 皖南医学院学报, 2002, 21(4): 269-270
作者姓名:卓栋  姜书传  韩杰  程庆水
作者单位:附属弋矶山医院泌尿外科,241001
基金项目:院中青年科研基金 (编号WK2 0 0 13 4)资助
摘    要:目的 探讨尿激酶型纤溶酶原激活物 (uPA)与肾细胞癌生物学行为之间的关系。方法 应用免疫组织化学方法检测 2 5例肾细胞癌组织中uPA蛋白水平的表达。结果 随着肾细胞癌分期的增高和转移的出现 ,uPA表达明显增高。结论 uPA表达在肾细胞癌组织中明显增高 ,uPA与肾细胞癌浸润转移密切相关

关 键 词:癌,肾细胞  尿激酶  免疫组织化学
文章编号:1002-0217(2002)04-0269-02
修稿时间:2002-03-20

Study on the Expression of Urokinase-type Plasminogen Activator in Renal Cell Carcinoma
Zhuo Dong,Jiang Shuchuan,Han Jie,et al. Study on the Expression of Urokinase-type Plasminogen Activator in Renal Cell Carcinoma[J]. Acta Academiae Medicinae Wannan, 2002, 21(4): 269-270
Authors:Zhuo Dong  Jiang Shuchuan  Han Jie  et al
Abstract:Objective To study the relationship between the urokinase type plasminogen activator(UPA) and the biological manner of renal cell carcinoma.Methods The ovalbumin in the tissue of renal cell carcinoma of 25 cases was investigated by using immunohistochemical technique.Results The level of UPA was significantly higher with the increase and metastasis of the different stages of renal cell carcinoma.Conclusion The expression of uPA increases in renal cell carcinoma, and uPA may contribute significantly to the invasion and metastasis renal cell carcinoma of invasion and metastasis .
Keywords:carcinoma  renal cell  urokinase  immunohistochemistry.
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