改良硬腭进路在中、晚期鼻咽癌综合治疗中的应用

目的 :探讨硬腭进路在中晚期鼻咽癌综合治疗中的作用。方法 :通过改进硬腭切口 ,保护腭大动脉 ,扩大鼻咽癌原发灶切除范围。术后给予常规化疗和预防性放疗。结果 :12例患者术后切口均Ⅰ期愈合。随访 6个月～ 5年均无复发 ,无腭瘘 ,语言及吞咽功能正常 ,未出现放射性脑病等。结论 :改进硬腭切口 ,可扩大鼻咽癌原发灶的切除范围 ,且不影响切口的愈合 ;术后给予化疗及预防性放疗 ,可获得良好的治疗效果

Clinical study on modified transpalatine radical operation for carcinoma of nasopharynx

OBJECTIVE: To evaluate the method of transpalatine surgical treatment of carcinoma of nasopharynx (NPC). METHOD: The artery palatine major was protected and the resection domain of primary lesion of NPC was expanded by modified hard palatine incision. Preventive radiotherapy and routine chemotherapy was given after the operation. RESULT: Twelve patients were in our report, five of II stage and seven of III stage. In all cases, the incisions in hard palatine were healing by first intention after the operations. The patients were followed up for six months to five years. None case was found relapse or palatal fistula. They all can swallow and speech as normal. Sequelae of radiotherapy was not found. CONCLUSION: Without affecting the healing of the incision, expanding the resective domain of primary lesion of NPC is possible by modified hard palatine incision, and the occurrence of sequelae of radiotherapy can be reduced by giving preventive radiotherapy.