急性脑梗死胰岛素抵抗和皮质醇变化的临床意义探讨

目的：探讨急性脑梗死患胰岛素抵抗和皮质醇变化的临床意义。方法：回顾分析64例脑梗死患空腹血糖、胰岛素及皮质醇，并与健康体检对照组比较。结果：脑梗死患血糖、胰岛素和皮质醇均较对照组高，ISI较对照组低、差异有显件；血糖、胰岛素和皮质醇在合并糖尿病较不合并糖尿病的要高、发生在半球较发生任基底节区要高，差异也有显性，结论：IR在于脑梗死患，并与梗死部位和有否合并糖尿病有关。皮质醇与IR相关。

To explore the clinical significance of insulin resistance and hydrocortisone changes in acute cerebral infarct

Objective To explore the clinical significance of insulin resistance(IR)and hydrocortisone in acute cerebral infarct. Methods The level of blood glucose on an empty stomach,free insulin and hydrocortisone of64cases acute cerebral infarct patients were analyzed retrospectively and compared to those in normal control group. Results the level of blood glucose on an empty stomach,free insulin and hydrocortisone were significantly higher and insulin sensibility index(ISI)was significantly lower in patients with acute cerebral infarct group than those in normal control group.They were also significantly higher in infarct taking place in hemisphere than those in basipodite area. Conclusion IR existed in acute cerebral infarct patients and which is correlative with infarct stop and accompanying diabetes mellitus.contisol is also correlative with IR.