| 16例婴儿巨细胞病毒肝炎的临床特点 |
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| 引用本文： | 曹金萍,方肖红. 16例婴儿巨细胞病毒肝炎的临床特点[J]. 医药论坛杂志, 2003, 24(14): 13-14 |
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| 作者姓名： | 曹金萍 方肖红 |
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| 作者单位： | 河南省洛阳市西工区人民医院儿科,洛阳市,471000 |
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| 摘 要： | 目的 观察婴儿巨细胞病毒(CMV)肝炎的临床特点及应用更昔络韦的治疗效果。方法 对2000年1月-2001年12月诊断CMV肝炎的16例婴儿进行分析，总结特点。应用更昔洛韦对其中14例进行治疗并观察其疗效及不良反应。结果 婴儿CMV肝炎的临床表现轻重不一，临床主要表现为黄胆、肝脾肿大及肝功能异常，同时可累及其它系统病变，重者可发展至肝硬化、腹水；应用更昔洛韦治疗83％(10／12)和79％(1l／14)的病历黄疸及血清谷丙转氨酶(ALT)下降，且无明显不良反应，随访肝功能、肝脾肿大逐渐恢复。结论 CMV肝炎大部分预后良好，应用更昔洛韦抗感染治疗具有良好的疗效。
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| 关 键 词： | 婴儿 巨细胞病毒 肝炎 临床特点 更昔络韦 治疗 |
| 修稿时间： | 2003-04-10 |
Characteristics of Clinical Manifestation of Cytomegalovirus Infant Hepatitis |
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| Cao Jinping,Fang Xiaohong. Characteristics of Clinical Manifestation of Cytomegalovirus Infant Hepatitis[J]. Journal of Medical Forum, 2003, 24(14): 13-14 |
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| Authors: | Cao Jinping Fang Xiaohong |
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| Abstract: | Objective Observing the clinical manifestation of cytomegalovirus(CMV) infant hepatitis and the therapeutic efficiency of Ganciclovir.Methods Analyze the features of 16 cases of CMV infant Hepatitis diagnosed from January,2000 to November,2001.Treat 14 cases with Ganciclovir to see the therapeutic efficiency and reaction.Results The clinical manifestation of the cases vary from light degree to heavy degree of Jaundice,hepatosplenomegaly,abnormal liver function which may result into other pathological changes.After treated with Ganciclovir,83%(10/12)and 79%(11/14)cases are found Jaundice and ALT decline and have no obvious bad reaction.The surveyed cases are found the gradual recovery from abnormal liver function and hepatosplenomegaly.Conclusion Most cases after the treatment have good reaction and have good therapeutic efficiency. |
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| Keywords: | infant hepatitis cytomegalovirus |
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