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药物基因组学应用于临床药学是个体化用药的必然趋势
引用本文:许景峰. 药物基因组学应用于临床药学是个体化用药的必然趋势[J]. 药学服务与研究, 2009, 9(3): 161-165
作者姓名:许景峰
作者单位:北京军区总医院药理科,北京,100007
摘    要:药物基因组学是人类进入功能基因组学研究后出现的一门新兴交叉学科,随着生物信息技术的飞速发展,药物基因组学应用于临床药学将是一个必然的趋势。临床药师作为药理学研究与临床实践间的信息中介,恰好成为从事药物基因组学研究的基本力量。将药物基因组学应用于临床药学是合理用药深入发展乃至实现个体化用药的必经之路.对于深入解释药物治疗的个体差异、减少药物不良反应、提高药物疗效等有重大意义。

关 键 词:药物基因组学  临床药学  合理用药  个体化用药

The application of pharmacogenomics in clinical pharmacy is the necessary path of individual medication
XU Jing-feng. The application of pharmacogenomics in clinical pharmacy is the necessary path of individual medication[J]. Pharmaceutical Care and Research, 2009, 9(3): 161-165
Authors:XU Jing-feng
Affiliation:XU Jing-feng (Department of Pharmacology, General Hospital of Beijing Military Region, Beijing 100007, China)
Abstract:Pharmacogenomics is a new interdiscipline after human stride into the era of functional genomics. With the rapid development of bioteebnology and bioinformation, application of pharrnacogenomies in clinical pharmacy will be an inevitable trend. As an information bridge between pharmacological research and clinical practice, clinical pharmacists have become the main force of pharmacogenomics research. Also, application of pharrnnacogenornics in clinical pharmacy is the necessary path to further development of rational drug use as well as individual medication, which has great significance in explanation of indi vidual variation after the medication, reducing adverse drug reactions and enhancing therapeutic effectiveness.
Keywords:pharrnacogenomics  clinical pharmacy  rational drug use  individual medication
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