水凝胶水解式微弹簧圈在颅内动脉瘤治疗中的应用

近年来随着介入栓塞技术的发展,各种用于动脉瘤栓塞的新型材料也不断涌现,极大的促进了血管内介入治疗的发展。MicroVention公司最新研制的水凝胶水解式微弹簧圈(Hydrocoil),采用了独特的水解方式,进一步丰富了颅内动脉瘤的血管内介入治疗的手段。Hydrocoil在传统铂金圈上附有可膨胀、不可吸收的水凝胶物质,可提高栓塞材料占动脉瘤的体积比。目前临床上刚开始使用,现将Hydrocoil的特性、临床前的动物实验和模型研究、临床治疗颅内动脉瘤的应用情况综述如下。

Hydrocoil for the treatment of intracranial aneurysms

In the recent few years,apart from the development of interventional technology,the development of new kinds material for packing intracranial aneurysms has hastened the promotion of endovascular interventional treatment greatly. Microvention company introduces lately Hydrocoil,a kind of hydro-agglutinated microspring coil which adopts a special hydrolink detachment technology,enriching the methods of endovascular treatment for cerebral aneurysms. Hydrocoil is a traditional platinum coil coated with expandable,unabsorble hydrogel material,which can improve the filling volume proportion of the aneurysm. At present it has been initially applied in clinic. This article summarizes the characteristics,the preclinical study,and the clinical application of Hydrocoil.(J Intervent Radiol,2007,16: 710-713)