| 肝酶灵注射液对大鼠慢性肝损伤的保护作用 |
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| 引用本文： | 张永明,黄亚非,陈建萍,邓子德,肖杰生.肝酶灵注射液对大鼠慢性肝损伤的保护作用[J].中药材,2003,26(2):111-112. |
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| 作者姓名： | 张永明 黄亚非 陈建萍 邓子德 肖杰生 |
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| 作者单位： | 1. 中山大学附属第三医院,广州,510630
2. 中山大学中山医学院,广州,510080 |
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| 基金项目： | 广州市重点技术攻关项目,编号为(JB02)97-Z46-067 |
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| 摘 要： | 目的：观察肝酶灵注射液对大鼠慢性肝损伤的保护作用。方法：采用颈后皮下注射CCl4致大鼠慢性肝损伤为模型，测定肝酶灵注射液对肝损伤大鼠AST、ALT、ALP和白蛋白／球蛋白的影响，同时对肝组织进行病理组织学检查。结果：肝酶灵注射液能降低慢性肝损伤大鼠血清AST、ALT、ALP含量，升高白蛋白／球蛋白，减轻肝组织的病理变化，保护肝组织的超微结构。结论：肝酶灵注射液对大鼠慢性肝损伤有显著的保护作用。
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| 关 键 词： | 肝酶灵注射液 慢性肝损伤 中药制剂 保护作用 动物实验 |
| 修稿时间： | 2002年1月16日 |
Protective Effect of Ganmeiling Injection on Chronic Hepatic Injury in Rats |
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| Zhang Yongming,Huang Yafei,Chen Jianping,Deng Zide,Xiao Jiesheng.Protective Effect of Ganmeiling Injection on Chronic Hepatic Injury in Rats[J].Jorunal of Chinese Medicinal Materials,2003,26(2):111-112. |
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| Authors: | Zhang Yongming Huang Yafei Chen Jianping Deng Zide Xiao Jiesheng |
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| Institution: | Affiliated Third Hospital, Sun Yat-sen University, Guangzhou 510630. |
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| Abstract: | Objective:To study protective effect of Injection Ganmeiling on chronic hepatic injury. Methods: The activity of AST, ALT and ALP in serum and histopathological change were determined in hepatic injury rats induced by CCL;. Results: Ganmeiling obviously inhibited the rising of AST, ALT and ALP in serum.The histopathological examination showed that Ganmeiling could alleviate the condition of necrosis and the degenration of hepatic cells. Conclusion: The results suggested that Ganmeiling could protect liver from hepatic injury induced by CCl4. |
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| Keywords: | Injection Ganmeiling Chronic hepatic injury Rat |
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