| 胃腺癌组织中cFLIP mRNA的表达及细胞凋亡检测 |
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| 引用本文： | 沈新生,张谢夫,陈奎生,薛艳格.胃腺癌组织中cFLIP mRNA的表达及细胞凋亡检测[J].郑州大学学报(医学版),2011,46(1):42-44. |
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| 作者姓名： | 沈新生 张谢夫 陈奎生 薛艳格 |
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| 作者单位： | 1. 郑州大学第一附属医院普通外科,郑州,450052
2. 郑州大学第一附属医院病理科,郑州,450052 |
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| 摘 要： | 目的:检测胃腺癌组织中cFLIP mRNA的表达及胃腺癌细胞的凋亡.方法:采用原位杂交技术检测45例胃腺癌、23例癌旁不典型增生及21例正常胃黏膜组织中cFLIP mRNA的表达;运用TUNEL法检测胃腺癌细胞凋亡情况,计算凋亡指数(AI).结果:胃腺癌组织中cFLIP mRNA的阳性表达率高于正常黏膜及不典型增生组织...
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| 关 键 词： | 胃腺癌 cFLIP 凋亡 |
Detection of cFLIP mRNA and cell apoptosis in gastric adenocarcinoma tissue |
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| SHEN Xinsheng
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ZHANG Xiefu
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CHEN Kuisheng
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XUE Yan'ge.Detection of cFLIP mRNA and cell apoptosis in gastric adenocarcinoma tissue[J].Journal of Zhengzhou University: Med Sci,2011,46(1):42-44. |
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| Authors: | SHEN Xinsheng ZHANG Xiefu CHEN Kuisheng XUE Yan'ge |
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| Institution: | SHEN Xinsheng1),ZHANG Xiefu1),CHEN Kuisheng2),XUE Yan'ge1)1)Department of General Surgery,the First Affiliated Hospital,Zhengzhou University,Zhengzhou 450052 2)Department of Pathology,Zhengzhou 450052 |
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| Abstract: | Aim:To detect the expression of cFLIP mRNA and apoptosis in gastric adenocarcinoma tissue.Methods:The expression of cFLIP mRNA in 45 cases of gastric adenocarcinoma,23 cases of gastric corresponding atypical hyperplasia,and 21 cases of normal gastric tissue was detected by using in situ hybridization.The apoptosis was examined by TUNEL assay.Results:Compared with the gastric adenocarcinoma group,the positive expression rates of cFLIP mRNA in normal gastric tissue and atypical hyperplasia tissue both decreas... |
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| Keywords: | gastric adenocarcinoma cFLIP apoptosis |
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