改良他汀序贯疗法治疗PCI患者的疗效观察

目的：探讨改良他汀序贯疗法对PCI患者的疗效。方法：将102例PCI患者随机分为观察组（改良他汀序贯疗法组,52例）和对照组（口服阿托伐他汀20mg/d,50例）,记录PCI术后6个月主要心血管事件,观察药物不良反应。结果：与对照组比较,观察组术后6个月主要心血管事件明显降低（P〈0.05）。随访期间,观察组和对照组肌毒性和肝毒性事件发生无差异。结论：改良他汀序贯疗法可减少PCI患者术后6个月主要心血管事件。

Effects of Statins Sequential Therapy in Patients with Percutaneous Coronary Intervention

Objective ： To investigate the effects of statins sequential therapy in patients with percutaneous coronary intervention（PCI）. Methods ： Totally 102 cases who received PCI were divided randomly into observed group（52 cases using sequential atorvastatin） and controlled group（50 eases using atorvastatin, 20 mg, daily）, the major adverse cardiovascular events（MACE） of all the patients collected six months after PCI were analyzed, and observing the drug-side effects. Results ：Comparing to the controlled group, the MACE in observed group decreased with statistical significance（P〈0.05）. There Was no significant difference between the observed and the control group for the muscle toxicity and hepatotoxieity. Conclusion ： Compared with conventional therapy, stains sequential therapy can significantly reduce the MACE in patients six months after PCI.