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文冠木正丁醇提取物的抗炎作用
引用本文:匡荣,包文芳,赵明宏,安宁飞,刘玉兰.文冠木正丁醇提取物的抗炎作用[J].沈阳药科大学学报,2001,18(1):53-56.
作者姓名:匡荣  包文芳  赵明宏  安宁飞  刘玉兰
作者单位:浙江省药品检验所,
摘    要:文冠木正丁醇提取物对二甲苯致小鼠耳肿胀、蛋清致大鼠足肿胀、角叉菜胶致小鼠足肿胀、醋酸致小鼠腹腔毛细血管通透性增加、小鼠羧甲基纤维素囊中白细胞游走、小鼠棉球肉芽肿生长均有显著的抑制作用 ,同样剂量下 ,文冠木正丁醇提取物对角叉菜胶致去双侧肾上腺小鼠足肿胀仍有显著的抑制作用 ,且对小鼠肾上腺重量及肾上腺中维生素C的含量没有明显影响

关 键 词:文冠木正丁醇提取物  抗炎作用  去肾上腺小鼠
文章编号:1006-2858(2001)01-0017-04
修稿时间:2000年8月30日

The anti-inflammatory effects of the n-butanol extract of Xanthoceras sorbifolia Bunge
Abstract:The anti-inflammatory effect of n-butanol extract of Xanthocerassorbifolia Bunge(BEX)was studied in this paper.The ear edema resulted from dimethyl benzene,paw edema induced by carrageenin,the increase of vascular permeability caused by acetic acid,the chemotaxis of WBC induced by CMC and the weight of cotton granuloma in mice and hind paw edema induced by fresh egg white in rats were inhibited significantly by ig BEX daily for 7 days,respectively.The carrageenin-induced paw edema was also inhibited markedly in adrenal-ectomiced mice.No changes in weight of adrenal and the concentration of vitamin C were observed,indicating that the anti-inflammatory effect of BEX was not related to pituitary-adrenal system.
Keywords:n  butanol extract of  Xanthoceras sorbifolia  Bunge  anti  inflammation    adrenal  ectomiced mi?
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