| 急性白血病早期死亡高危因素的回归分析 |
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| 引用本文： | 王军,林果为,王小钦,王倩,黄前川,熊金元. 急性白血病早期死亡高危因素的回归分析[J]. 临床血液学杂志, 1998, 11(2): 66-67 |
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| 作者姓名： | 王军 林果为 王小钦 王倩 黄前川 熊金元 |
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| 作者单位： | 上海医科大学!广州军区武汉总医院血液科，430070，上海医科大学华山医院血液科，上海医科大学华山医院血液科，上海医科大学华山医院血液科，广州军区武汉总医院血液科，广州军区武汉总医院血液科 |
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| 摘 要： | 采用病例对照研究，对11年上海地区27家医院2867例急性白血病（AL）住院患者早期死亡的高危同素进行Lognistic回归分析。结果：出血、感染和多脏器衰竭是AL死亡的主要原因。全反式维甲酸（ATRA）的应用，降低了急性早幼粒细胞白血病（APL）早期病死率。早期死亡的高危因素为：年龄≥60岁或≤1岁，发病时伴有明显出血、外用血白细胞＞100X109／L、BPC＜50X109／L。结论：针对上述高危因素采取相应防治措施，降低AL的早期病死率十分必要。
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| 关 键 词： | 白血病.急性 早期死亡 回归 |
Logistic Regression Analysis for High Risk Factors of Early Death in Acute Leukemia |
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| Abstract: | In order to know high risk factors of early death of acute leukemia (AL),the total of 2 867 cases with AL were collected from 27 hospitals in Shanghai area,Case-control study were used for design. Logistic regression were used to analyze the risk factors. The early death rates of AL within 30 days were 12%. The rates were higher in elderly patients and children(age of less that of 1 year old),Bleeding,infection and multiple organs failure were the main causes of early death- The high risk factors for early death within 30 days were the age of more than 60 years old or less than 1 year old, bleeding, DIC, enlargement of liver, peripheral WBC> 100 X109/L, BPC< 50 X 109/L, fever infection and AML |
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| Keywords: | Acute leukemia Early death Logistic regression |
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