新生儿缺血缺氧性脑病CT表现与临床预后分析

目的 探讨新生儿缺血缺氧性脑病（HIE）的CT分度与预后关系。方法 回顾性分析98例新生儿缺血缺氧性脑病的CT表现和临床随访，总结CT诊断HIE的价值。按HIE严重程度将所有患者的病变分为3度。结果 在98例中CT诊断轻度HIE32例，中度HIE48例，重度HIE18例。跟踪随访HIE所致脑低密度灶在生后3个月内吸收消失;19例3～6个月出现外部性脑积水，1岁以后，外部性脑积水消失;3个月后部分病例可见脑室周围白质软化灶，重度HIE在2个月内可引起脑软化和脑萎缩。结论 HIE的CT分度与临床预后有密切关系。

CT findings and prognosis of hypoxic-ischemic encephalopathy in neonates

Objective To investigate the correlation between CT grading and prognosis of hypoxic-ischemic encephalopathy(HIE)in neonates.Methods Ninety-eight neonates with HIE whose CT findings and followed-up results were retrospectively analyzed together with the diagnostic value of CT.The lesions of HIE in all patients were divided into three grades according to their severity.Results Among 98 cases,CT demonstrated 32 mild HIE,48 moderate HIE and 8 severe HIE.The clinical follow-up showed that,the hypodense foci induced by HIE were absorbed and disappeared completely within 3 months after birth.Nineteen neonates presented external hydrocephalus at 3-6 months after birth and then that was disappeared after one year of age.At 3 months or more after birth,HIE in part neonates might cause the periventricular leukomalacia,while severe HIE might cause the cerebral malacia and atrophy within 2 months after birth.Conclusion The prognosis of HIE is closely related to the CT grading.