Inflammatory bowel disease |
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Authors: | Morten H. Vatn Arne K. Sandvik |
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Affiliation: | 1. Institute of Clinical Medicine, Campus Ahus, University of Oslo, Oslo, Norway;2. Department of Transplantation and Cancer, Section of Gastroenterology, Oslo University Hospital, Rikshospitalet, Norwaym.h.vatn@medicine.uio.no;4. Department of Gastroenterology and Hepatology, St. Olav’s University Hospital, Trondheim, Norway;5. Department of Cancer Research and Molecular Medicine, Faculty of Medicine, Norwegian University of Science and Technology, Trondheim, Norway;6. Centre of Molecular Inflammation Research, Norwegian University of Science and Technology, Trondheim, Norway |
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Abstract: | AbstractScandinavian researchers have contributed to the present understanding of inflammatory bowel disease (IBD). Important epidemiological data and family risk factors have been reported from all the Nordic countries, original twin studies mainly from Denmark and Sweden, and relationships to cancer and surgery mostly from Sweden. In collaboration with the industry, development of medical compounds was for a long time in the front line of international research, and the Scandinavian countries participated in the clinical breakthrough of biologic treatment. At present, many Nordic centers are working in the forefront of IBD research. An increasing number of young investigators have entered the scene along with the extended distribution of University clinics and research laboratories in these countries. This presentation of IBD gives a brief overview in the fields of clinical epidemiology and molecular biology. Many areas are covered by International collaborations with partners from Nordic centers. IBD was a topic focused by the founders of Scandinavian Journal of Gastroenterology. After 50 years one may state that the journal’s history reflects important pieces of scientific knowledge within these diseases. The early scope of Johannes Myren for IBD was shown through his work in the original World Association of Gastroenterology (OMG), and after 50 years we can clearly support the view that global perspectives in IBD are increasingly important. |
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Keywords: | clinical Crohn’s disease environment epidemiology genetics inflammatory bowel diseases molecular biology treatment ulcerative colitis |
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