颅骨成形术后颅内出血的相关危险因素分析

目的分析颅骨成形术后颅内出血的相关危险因素。 方法回顾性分析解放军总医院第三医学中心神经创伤外科自2010年11月至2018年11月收治的278例行颅骨成形术患者的临床资料，按照术后颅内是否出血将患者分为出血组和未出血组。采用单因素分析和多因素Logistic回归分析确定颅骨成形术后颅内出血的独立影响因素。 结果278例患者颅骨成形术后颅内出血12例，颅内出血发生率为4.3%。单因素分析显示：缺损面积及颅骨缺损时间与颅内出血发生相关，差异有统计学意义（P<0.05），Logistic多因素回归分析显示：颅内缺损面积（≥100 cm²）是颅骨成形术后颅内出血的独立危险因素（P<0.05）。 结论颅骨缺损面积是影响颅骨成形术后颅内出血的临床危险因素，评估上述指标对颅骨成形术后颅内出血有重要的临床意义。

Analysis of risk factors for intracranial hemorrhage after cranioplasty

ObjectiveTo analyze the risk factors of intracranial hemorrhage after cranioplasty. MethodsA total of 278 patients with skull defect undergoing cranioplasty admitted to Department of Neurosurgery, Third Medical Center of PLA Gerneral Hospital from November 2010 to November 2018 were analyzed retrospectively. Patients were divided into 2 groups according to whether there was intracranial hemorrhage or not. Univariate analysis and multivariate Logistic regression analysis were used to identify the independent risk factor of epilepsy after cranioplasty. ResultsOf the 278 patients, 12 experienced intracranial hemorrhage after cranioplasty with an incidence of 4.3%. Univariate analysis showed that the area of defect and the time of skull defect were related to the occurrence of intracranial hemorrhage, the difference was statistically significant (P<0.05). multivariate Logistic regression analysis showed that the area of intracranial defect (≥100 cm²) was an independent risk factor of intracranial hemorrhage after cranioplasty (P<0.05). ConclusionThe area of skull defect is the clinical risk factor of intracranial hemorrhage after cranioplasty. It is of important clinical significance for intracranial hemorrhage after cranioplasty to focus on the above indexe assessment.