| 新型抗癫痫药物临床应用研究 |
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| 引用本文： | 王栋梁,宋海栋,许可,刘如恩. 新型抗癫痫药物临床应用研究[J]. 中国医学科学院学报, 2019, 41(4): 566-571. DOI: 10.3881/j.issn.1000-503X.11500 |
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| 作者姓名： | 王栋梁 宋海栋 许可 刘如恩 |
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| 作者单位： | 北京大学人民医院神经外科,北京 100044 |
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| 基金项目： | 脑科学与类脑研究北方科学中心项目(Z181100001518005);北大种子交叉基金(BMU2018MI001) |
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| 摘 要： | 癫痫发病率高且病因复杂,治疗相对棘手。新诊断的癫痫患者,若接受规范、合理的抗癫痫药物治疗,大约70%的患者癫痫发作可以得到控制。近年来,新型抗癫痫药物逐渐问世,作为目前抗癫痫药物的有效补充,为癫痫患者提供了更多的选择机会。掌握新型抗癫痫药物的药动学、疗效、耐受性等特点,有助于为患者提供安全、正确、合理、规范的治疗。
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| 关 键 词： | 新型抗癫痫药物 药代动力学 儿童癫痫 |
| 收稿时间： | 2019-04-29 |
Clinical Application of New Antiepileptic Drugs |
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| WANG Dongliang,SONG Haidong,XU Ke,LIU Ruen. Clinical Application of New Antiepileptic Drugs[J]. Acta Academiae Medicinae Sinicae, 2019, 41(4): 566-571. DOI: 10.3881/j.issn.1000-503X.11500 |
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| Authors: | WANG Dongliang SONG Haidong XU Ke LIU Ruen |
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| Affiliation: | Department of Neurosurgery,Peking University People’s Hospital,Beijing 100044,China |
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| Abstract: | Epilepsy has high incidence and complex etiologies,and its treatment remains challenging.For around 70% of people with epilepsy,seizures can be controlled after proper antiepileptic treatment.The availability of some new antiepileptic drugs in recent years has offered new options for epileptic patients.A solid knowledge on the pharmacokinetics,efficacy,and tolerability profiles of these new antiepileptic drugs will help to provide safe,proper,reasonable,and standardized treatment for patients. |
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| Keywords: | new antiepileptic drugs pharmacokinetics pediatric patients with epilepsy |
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