不同探针超声碎石在尿路结石患者中的疗效及对炎症因子的影响研究

目的 探讨点触式探针和平面探针在尿路结石患者碎石治疗中的效果及对患者血清炎症因子的影响。方法 将96例尿路结石患者分为点触式碎石组及平面碎石组，点触式碎石组患者接受点触式超声探针碎石治疗，平面碎石组患者接受平面超声探针碎石治疗，如遇无法击碎的结石时，两组患者均联合气压弹道碎石。于碎石前(T1)、治疗1 d后(T2)及治疗5 d后(T3)评估两组患者血清炎症因子水平；于碎石后记录碎石时间、结石体积及碎石速度。结果 点触式探针的碎石时间明显优于平面探针(P<0.01)；治疗后，两组患者的血清炎症因子水平均明显升高(P<0.01)，但在治疗5 d后(T3)，点触式碎石组患者的血清炎症因子基本恢复至正常水平，平面碎石组患者的血清炎症因子水平仍较碎石前高，两组比较差异有统计学意义(P<0.01)，且点触碎石组患者的并发症的发生次数少于平面碎石组患者(P<0.01)。结论 点触式探针比平面探针在超声碎石中有更好的应用效果。

Effect of different probe ultrasonic lithotripsy on urinary calculi and inflammatory factors

Objective  To investigate the effects of different probes on the lithotripsy of patients with urinary stones and the serum inflammatory factors. Methods   From April 2016 to April 2018, 96 patients with urinary stones who were hospitalized in our hospital were randomly divided into the point-contact group and the plane group, patients in the point-contact group treated with point-contact probe gravel, and the patients in the plane group received the gravel of plane probe.Serum inflammatory factors were evaluated before treatment(T1), 1 day after treatment(T2) and 5 days after treatment(T3).After gravel, the therapy time, stone volume and speed of gravel were recorded. The complications of the two groups were evaluated after treatment.Results  In this study, the gravel speed of the point-contact probe was almost 1.6 times compared with the plane probe, the gravel speed was significantly faster(P<0.01), and the gravel time of the point-contact probe was significantly better than the plane probe(P<0.01).After treatment, the patients of two groups were significantly higher serum levels of inflammatory factors(P<0.01). But in the T3, serum inflammatory factors returned to normal in the point-contact probe group, serum inflammatory factors in the plane probe group were still higher(P<0.01). Conclusions   Compared with the plane probe, the point-contact probe has good effect in the application of ultrasound lithotripsy.