药学干预影响慢性阻塞性肺疾病临床治疗结局评价

目的：评价药学路径干预慢性阻塞性肺疾病（COPD）患者的临床效果。方法：选取2017年4月至2017年8月在南昌大学第一附属医院呼吸科住院患者90例，随机分为药学干预组45例和常规组45例，药学干预组实施药物指导、用药知识教育等药学干预，常规组未开展药学干预，比较两组患者药物的使用情况、药物不良事件发生率（ADE）、患者满意度、健康教育知晓率等。结果：与常规组相比，药学干预组患者的用药依从性、满意度、健康教育知晓率均更高，而用药偏差则较前者更低（P<0.01）。结论：遵循药学服务路径对于接受多药治疗的COPD住院患者进行全程化的药学干预，可改善患者的用药依从性、满意度、健康教育知晓情况，降低用药偏差，为临床药师药学路径应用提供参考。

Pharmaceutical intervention in evaluation of clinical pathway for patients with chronic obstructive pulmonary disease effect

OBJECTIVE To evaluate the clinical effect of pharmaceutical pathway intervention on patients with chronic obstructive pulmonary disease (COPD). METHODS From April 2017 to August 2017, 90 patients were admitted to the Department of Respiratory Medicine of the First Affiliated Hospital of Nanchang University. They were randomly divided into pharmaceutical intervention group (45 cases) and control group (45 cases). The pharmaceutical intervention group received pharmaceutical intervention such as drug guidance and knowledge education of drug use while the control group did not received any kind of pharmaceutical intervention. The use of drugs, the incidence of adverse drug events (ADE), patient satisfaction, and awareness of health education were compared between the two groups. Results:Compared with the control group, the compliance, satisfaction and awareness rate of health education in the pharmaceutical intervention group were higher (P<0.05 or P<0.01), and the medication deviation was significantly lower (P<0.01). CONCLUSION The whole-course pharmacy intervention following the pharmacy service pathway can improve the compliance, satisfaction and health education awareness of COPD patients, reduce the deviation of drug use, and provide reference regarding pharmacy path application for clinical pharmacists.