18F-FDG PET/CT检测卵巢癌术后CA125升高病人转移或复发的效果分析

目的探讨18F-FDG PET/CT（PET/CT）在检测卵巢癌术后血CA125升高病人转移或复发的效果。方法回顾32例行PET/CT检查的卵巢癌术后血CA125升高疑似转移或复发的病人，行PET/CT检查与传统影像学（CT或超声）结果比较，经再次手术或穿刺活检的病理结果或结合临床及其他影像学资料随访结果确诊。结果PET/CT示转移或复发常见部位依次是盆腔、腹腔、胸腔；转移器官有淋巴结、肺、肝、脾脏和骨骼等；其中转移或复发病灶部位SUVmax均高于正常参考值。PET/CT的敏感度及准确度均高于传统影像学（P < 0.05和P < 0.01），特异度与传统影像学差异无统计学意义（P>0.05）。结论PET/CT检查在卵巢癌术后转移或复发的检测中具有较高的诊断效能。

Application value of 18F-FDG PET/CT in the detection of metastasis or recurrence of ovarian cancer patients with CA125 increasing after operation

ObjectiveTo explore the value of 18F-FDG PET/CT in detecting the metastasis or recurrence of ovarian cancer patients with serum CA125 increasing after surgery.MethodsThe clinical data of 32 suspected metastasis or recurrence ovarian cancer patients with postoperative CA125 level increasing were retrospectively analyzed.The results of 18F-FDG PET/CT were compared with traditional imaging(CT or ultrasound).The diagnosis results of patients were confirmed by the pathological examination of reoperation or puncture biopsy, and following-up data of clinical and imaging data.ResultsThe results of 18F-FDG PET/CT showed that the common sites of metastasis or recurrence were pelvis, abdominal cavity and thorax in turn, and the metastasis organs included the lymph node, lung, liver, spleen and bone.The SUVmax value of metastatic or recurrent lesions was higher than the normal reference value.The sensitivity and accuracy of 18F-FDG PET/CT were higher than those of traditional imaging(P < 0.05 and P < 0.01), but the difference of the specificity between two methods was not statistically significant(P>0.05).Conclusions18F-FDG PET/CT has a high diagnostic efficacy in the metastasis or recurrence of ovarian cancer after operation.