2019冠状病毒病(COVID-19)疑似患者合并焦虑和抑郁的临床分析

目的: 分析2019冠状病毒病（COVID-19）疑似患者伴发焦虑、抑郁的危险因素以便早期干预以改善临床预后。方法: 收集2020年1月31日至2月22日兰州大学第二医院发热隔离病房收治的COVID-19疑似患者76例，收集其临床资料并采用汉密尔顿焦虑量表评测患者焦虑情况，汉密尔顿抑郁量表评测患者抑郁情况，行多因素Logistic回归分析COVID-19疑似患者出现焦虑或抑郁的危险因素。结果: 女性患者较男性患者更易伴发焦虑（OR=3.206，95%CI：1.073~9.583，P < 0.05）和抑郁情绪（OR=9.111，95%CI：2.143~38.729，P < 0.01）；患者存在已知疫区及疫区人员接触史更容易伴发抑郁情绪（OR=3.267，95%CI：1.082~9.597，P < 0.05）。结论: 在COVID-19疑似患者隔离治疗期间，对于存在已知疫区及疫区人员接触史的女性患者应该早期进行心理干预，必要时提早给予药物治疗，以改善患者预后。

Clinical analysis of suspected COVID-19 patients with anxiety and depression

Objective: To explore the risk factors of anxiety and depression in patients with suspected coronavirus disease 2019 (COVID-19) so as to achieve early intervention and better clinical prognosis. Methods: Seventy-six patients with suspected COVID-19 in fever isolation wards of Second Hospital of Lanzhou University were enrolled From January 31, 2020 to February 22, 2020. Their clinical baseline data were collected. The anxiety of patients was assessed by Hamilton Anxiety Scale, and the depression of patients was assessed by Hamilton Depression Scale. Multivariate Logistic regression analysis was performed to explore the risk factors of anxiety and depression in these patients. Results: Female patients are more likely to have anxiety (OR=3.206, 95%CI:1.073-9.583, P < 0.05) and depression (OR=9.111, 95%CI:2.143-38.729, P < 0.01) than male patients; patients with known contact history of epidemic area and personnel in epidemic area are more likely to have depression (OR=3.267, 95%CI:1.082-9.597, P < 0.05). Conclusion: During the isolation treatment of suspected COVID-19 patients, early psychological intervention should be carried out for the female patients with known contact history of epidemic area and personnel in epidemic area, and drug treatment should be given in advance if necessary.