超声引导融合虚拟CT导航射频治疗高危部位原发性肝癌

目的 探讨实时超声引导融合虚拟CT导航下射频消融治疗高危部位原发性肝癌的价值。方法 前瞻性收集2017年1月至2018年6月于广西医科大学第一附属医院治疗的80例高危部位原发性肝癌患者的临床资料，分为实时超声引导融合虚拟CT导航下射频消融治疗组（观察组，n=42）和单纯超声引导治疗组（对照组，n=38），比较两组患者的定位率、消融率、并发症发生情况和复发进展率。结果 观察组一次定位成功率和两次消融率均高于对照组（P<0.05），但复发进展率低于对照组（2.38% vs 21.05%，P=0.011）；两组患者的并发症发生率差异无统计学意义（2.38% vs 5.26%，P=0.602）。结论 高危部位原发性肝癌超声引导融合虚拟CT导航下射频消融治疗的疗效优于单纯超声引导治疗。

Ultrasound guided fusion virtual CT navigation radiofrequency therapy for high risk sites of primary liver cancer

Objective To evaluate the value of real-time ultrasound guided fusion and virtual CT guided radiofrequency ablation （RFA） in the treatment of primary liver cancer in high-risk sites. Methods Clinical data of 80 patients with high-risk primary liver cancer who were treated in the First Affiliated Hospital of Guangxi Medical University from January 2017 to June 2018 were collected prospectively and divided into real-time ultrasound guided fusion virtual CT navigation radiofrequency ablation treatment group （observation group，n=42） and ultrasound guided treatment group（control group，n=38）. The localization rate，ablation rate，compli-cations，and recurrence rate were compared between the two groups. Results The initial success rate and the two ablation rates of the observation group were higher than those of the control group （P<0.05），but the recurrence rate was lower than that of the control group（2.38% vs 21.05%，P=0.011）. There was no significant difference in the incidence of complications between the two groups（2.38% vs 5.26%，P=0.602）. Conclusion High-risk primary liver cancer ultrasound guided fusion virtual CT navigation radiofrequency ablation is better than ultrasound guided therapy.