经颅直流电刺激联合言语训练对脑梗死后失语症的治疗效果

目的研究经颅直流电刺激(tDCS)联合言语训练对脑梗死后失语症病人的治疗作用。方法选取脑梗死后失语症病人100例，按照随机数字表法分常规组和联合组，各50例。常规组予以言语训练，联合组予以tDCS联合言语训练。比较2组病人干预前后的西部失语症测试(WAB)评分、日常生活交流能力量表(CADL)评分、简易智力状态检查量表(MMSE)评分和图片命名测试结果，并通过波士顿诊断性失语症检查法分级评价病人治疗效果。结果联合组病人治疗总有效率为94.00%(47/50)，明显高于常规组的74.00%(37/50)(P＜0.01)。干预前，2组病人WAB评分、CADL评分、MMSE评分和图片命名测试结果差异均无统计学意义(P＞0.05)；干预后，联合组病人WAB各子测试评分、CADL评分、MMSE评分均高于常规组(P＜0.05~P＜0.01)，图片命名测试中训练和未训练图片的正确命名数均明显多于常规组(P＜0.01)。结论tDCS联合言语训练可改善脑梗死后失语症病人病情严重程度，改善病人言语功能、日常生活交流能力和认知功能，激活、协调大脑神经网络系统，改善病人命名泛化效应和固化效应。

Effect of transcranial direct current stimulation combined with speech training in the treatment of aphasia after cerebral infarction

ObjectiveTo study the effects of transcranial direct current stimulation(tDCS) combined with speech training in the treatment of aphasia after cerebral infarction.MethodsA total of 100 patients with aphasia after cerebral infarction were randomly divided into the regular group and combined group(50 cases in each group).The speech training in regular group was implemented, and the tDCS combined speech training in combined group was implemented.The western aphasia battery(WAB) score, daily life communication skills scale(CADL) score, mini-mental state examination scale(MMSE) score and picture naming test results were compared bewteen two groups before and after the intervention.ResultsThe total effective rate in combined group(94.00%) was significantly higher than that in regular group(74.00%) (P＜0.01).Before intervention, the differences of the WAB score, CADL score, MMSE score and results of picture naming test between two groups were not statistically significant(P＞0.05).After intervention, the WAB score, CADL score and MMSE score in combined group were higher than those in regular group(P＜0.05 to P＜0.01), and the correct number of training pictures and untraining pictures in combined group were more than that in regular group(P＜0.01).ConclusionsThe tDCS combined with speech training can improve the severity of aphasia patients after cerebral infarction, their speech function, daily communication ability, cognitive function, activate and coordinate the brain neural network system and patient′s generalization effect and curing effect.